Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure Analysis

Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure Analysis

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http://www.wikidata.org/entity/Q27667321
Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndromeCresyl saligenin phosphate, an organophosphorus toxicant, makes covalent adducts with histidine, lysine, and tyrosine residues of human serum albuminAutoantibodies to nervous system-specific proteins are elevated in sera of flight crew members: biomarkers for nervous system injury.Cresyl saligenin phosphate makes multiple adducts on free histidine, but does not form an adduct on histidine 438 of human butyrylcholinesterase.Exposure to tri-o-cresyl phosphate detected in jet airplane passengers.Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and cAnalytical approaches for monitoring exposure to organophosphorus and carbamate agents through analysis of protein adducts.Quantitation of ortho-cresyl phosphate adducts to butyrylcholinesterase in human serum by immunomagnetic-UHPLC-MS/MS.Acetylcholinesterase and neuropathy target esterase activities in 11 cases of symptomatic flight crew members after fume events.Novel selective and irreversible mosquito acetylcholinesterase inhibitors for controlling malaria and other mosquito-borne diseases.Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and molecular dynamics studies.Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins and Peptides Independent of Surrounding Amino Acids.Analysis of the neurotoxic effects of neuropathic organophosphorus compounds in adult zebrafish.Molecular modeling evidence for His438 flip in the mechanism of butyrylcholinesterase hysteretic behavior.Tubulin and Tau: Possible targets for diagnosis of Parkinson's and Alzheimer's diseases.Aerotoxisches Syndrom
P2860

Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure Analysis

Item
http://www.wikidata.org/entity/Q27667321
description
2011 nî lūn-bûn
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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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Reaction of Cresyl Saligenin P ...... , and X-ray Structure Analysis
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P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932