The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites
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Botulinum Neurotoxin Serotype C Associates with Dual Ganglioside Receptors to Facilitate Cell EntryStructure of dual receptor binding to botulinum neurotoxin BPlasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence SystemCrystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and IIBotulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins.Intranasal vaccination with an engineered influenza virus expressing the receptor binding subdomain of botulinum neurotoxin provides protective immunity against botulism and influenza.Diverse binding modes, same goal: The receptor recognition mechanism of botulinum neurotoxin.CRISPR/Cas9-Mediated Genomic Deletion of the Beta-1, 4 N-acetylgalactosaminyltransferase 1 Gene in Murine P19 Embryonal Carcinoma Cells Results in Low Sensitivity to Botulinum Neurotoxin Type C.The receptor binding domain of botulinum neurotoxin serotype C binds phosphoinositides.Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature.Engineering Botulinum Neurotoxin C1 as a Molecular Vehicle for Intra-Neuronal Drug Delivery.The blockade of the neurotransmitter release apparatus by botulinum neurotoxins.Detection, differentiation, and identification of botulinum neurotoxin serotypes C, CD, D, and DC by highly specific immunoassays and mass spectrometry.Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology.P19 embryonal carcinoma cells exhibit high sensitivity to botulinum type C and D/C mosaic neurotoxins.Retargeting the Clostridium botulinum C2 toxin to the neuronal cytosol.Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission.A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells.Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN)Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin.Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E.Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency.Engineering Botulinum Toxins to Improve and Expand Targeting and SNARE Cleavage Activity
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P2860
The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The biological activity of bot ...... s of ganglioside binding sites
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The biological activity of bot ...... s of ganglioside binding sites
@en
The biological activity of bot ...... s of ganglioside binding sites
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type
label
The biological activity of bot ...... s of ganglioside binding sites
@ast
The biological activity of bot ...... s of ganglioside binding sites
@en
The biological activity of bot ...... s of ganglioside binding sites
@nl
prefLabel
The biological activity of bot ...... s of ganglioside binding sites
@ast
The biological activity of bot ...... s of ganglioside binding sites
@en
The biological activity of bot ...... s of ganglioside binding sites
@nl
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P2860
P3181
P1476
The biological activity of bot ...... s of ganglioside binding sites
@en
P2093
Andreas Pich
Hans Bigalke
Jasmin Strotmeier
Shenyan Gu
Stefan Mahrhold
Stephan Jutzi
Thomas Binz
Timo Eichner
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P304
P3181
P356
10.1111/J.1365-2958.2011.07682.X
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P577
2011-06-02T00:00:00Z