about
The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteinsGlobal-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo ModifiersXeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulationThe Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP)2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibitionKey steps in ERAD of luminal ER proteins reconstituted with purified componentsThe budding yeast Cdc48(Shp1) complex promotes cell cycle progression by positive regulation of protein phosphatase 1 (Glc7).Mutations in the Human AAA+ Chaperone p97 and Related DiseasesThe general definition of the p97/valosin-containing protein (VCP)-interacting motif (VIM) delineates a new family of p97 cofactorsEmerging functions of the VCP/p97 AAA-ATPase in the ubiquitin systemAltered cofactor regulation with disease-associated p97/VCP mutationsControl of p97 function by cofactor bindingStructural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated DegradationA non-canonical role of the p97 complex in RIG-I antiviral signalingSystematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.A Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopyThe ubiquitin regulatory X (UBX) domain-containing protein TUG regulates the p97 ATPase and resides at the endoplasmic reticulum-golgi intermediate compartment.Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.Complex of Fas-associated factor 1 (FAF1) with valosin-containing protein (VCP)-Npl4-Ufd1 and polyubiquitinated proteins promotes endoplasmic reticulum-associated degradation (ERAD)Structural and functional deviations in disease-associated p97 mutants.Structure and function of the AAA+ ATPase p97/Cdc48p.Role of p97/VCP (Cdc48) in genome stability.A Dynamic molecular basis for malfunction in disease mutants of p97/VCP.The p97-UFD1L-NPL4 protein complex mediates cytokine-induced IκBα proteolysis.p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions.Protein quality control in the ER: balancing the ubiquitin checkbook.Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy.CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination.The p97-FAF1 protein complex reveals a common mode of p97 adaptor binding.The Interplay of Cofactor Interactions and Post-translational Modifications in the Regulation of the AAA+ ATPase p97.Structure and recognition of polyubiquitin chains of different lengths and linkage.Valosin-containing protein (VCP)-Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor.The AAA+ ATPase p97, a cellular multitool.Termination of DNA replication forks: "Breaking up is hard to do".Structural basis for nucleotide-modulated p97 association with the ER membrane.Interaction between the AAA+ ATPase p97 and its cofactor ataxin3 in health and disease: Nucleotide-induced conformational changes regulate cofactor binding.Structural insights into the interaction of human p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Hierarchical binding of cofactors to the AAA ATPase p97
@ast
Hierarchical binding of cofactors to the AAA ATPase p97
@en
Hierarchical binding of cofactors to the AAA ATPase p97
@nl
type
label
Hierarchical binding of cofactors to the AAA ATPase p97
@ast
Hierarchical binding of cofactors to the AAA ATPase p97
@en
Hierarchical binding of cofactors to the AAA ATPase p97
@nl
prefLabel
Hierarchical binding of cofactors to the AAA ATPase p97
@ast
Hierarchical binding of cofactors to the AAA ATPase p97
@en
Hierarchical binding of cofactors to the AAA ATPase p97
@nl
P3181
P1433
P1476
Hierarchical binding of cofactors to the AAA ATPase p97
@en
P2093
Alexander Buchberger
P304
P3181
P356
10.1016/J.STR.2011.03.018
P577
2011-06-08T00:00:00Z