Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope
about
Shake, rattle, and roll: Impact of the dynamics of flavivirus particles on their interactions with the hostDevelopment, characterization and application of monoclonal antibodies against Brazilian Dengue virus isolatesPossible future monoclonal antibody (mAb)-based therapy against arbovirus infectionsDeconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and ImmunityDengue structure differs at the temperatures of its human and mosquito hostsStructural Changes in Dengue Virus When Exposed to a Temperature of 37 CA potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surfaceIdentification of a New Broadly Cross-reactive Epitope within Domain III of the Duck Tembusu Virus E ProteinDengue: knowledge gaps, unmet needs, and research prioritiesA single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesisThe Antigenic Structure of Zika Virus and Its Relation to Other Flaviviruses: Implications for Infection and ImmunoprophylaxisInnate immunity to dengue virus infection and subversion of antiviral responses.Combined effects of the structural heterogeneity and dynamics of flaviviruses on antibody recognition.Cross-reactivities between human IgMs and the four serotypes of dengue virus as probed with artificial homodimers of domain-III from the envelope proteins.The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope proteinDirect and indirect interactions in the recognition between a cross-neutralizing antibody and the four serotypes of dengue virus.Dissection of antibody specificities induced by yellow fever vaccinationAtomic-level functional model of dengue virus Envelope protein infectivity.The type-specific neutralizing antibody response elicited by a dengue vaccine candidate is focused on two amino acids of the envelope protein.Detection of serotype-specific antibodies to the four dengue viruses using an immune complex binding (ICB) ELISAPotent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement.Comprehensive mapping of functional epitopes on dengue virus glycoprotein E DIII for binding to broadly neutralizing antibodies 4E11 and 4E5A by phage display.Genotypic Differences in Dengue Virus Neutralization Are Explained by a Single Amino Acid Mutation That Modulates Virus Breathing.Single Neutralizing Monoclonal Antibodies Targeting the VP1 GH Loop of Enterovirus 71 Inhibit both Virus Attachment and Internalization during Viral EntryDengue virus antibody database: Systematically linking serotype-specificity with epitope mapping in dengue virus.A game of numbers: the stoichiometry of antibody-mediated neutralization of flavivirus infection.Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection.Epitope Identification and Application for Diagnosis of Duck Tembusu Virus Infections in Ducks.Conformational changes in intact dengue virus reveal serotype-specific expansion.B cell response and mechanisms of antibody protection to West Nile virus.Electron microscopy: essentials for viral structure, morphogenesis and rapid diagnosis.Paradoxical role of antibodies in dengue virus infections: considerations for prophylactic vaccine development.Enhancing dengue virus maturation using a stable furin over-expressing cell lineMolecular basis of antibody-mediated neutralization and protection against flavivirus.Vaccines licensed and in clinical trials for the prevention of dengue.Complexity of Human Antibody Response to Dengue Virus: Implication for Vaccine Development.A humanized monoclonal antibody neutralizes yellow fever virus strain 17D-204 in vitro but does not protect a mouse model from diseaseA novel mechanism of antibody-mediated enhancement of flavivirus infection.Structural Basis of Zika Virus-Specific Antibody Protection.Molecular docking NS4B of DENV 1-4 with known bioactive phyto-chemicals.
P2860
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P2860
Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@ast
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@en
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@nl
type
label
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@ast
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@en
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@nl
prefLabel
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@ast
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@en
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@nl
P2093
P2860
P50
P3181
P1433
P1476
Structural Basis of Differenti ...... t Recognizes a Cryptic Epitope
@en
P2093
Christopher A Nelson
Daved H Fremont
Melissa A Edeling
S Kyle Austin
Syd Johnson
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1002930
P577
2012-01-01T00:00:00Z