Serine is a natural ligand and allosteric activator of pyruvate kinase M2
about
Warburg effect and translocation-induced genomic instability: two yeast models for cancer cellsMetabolomic analysis of human cirrhosis, hepatocellular carcinoma, non-alcoholic fatty liver disease and non-alcoholic steatohepatitis diseasesPyruvate Kinase M2: A Potential Target for Regulating InflammationPyruvate kinase: Function, regulation and role in cancerAmino acid management in cancerSerine, glycine and one-carbon units: cancer metabolism in full circleIs cancer a metabolic disease?Serine and glycine metabolism in cancerPyruvate kinase M2 at a glanceFueling immunity: insights into metabolism and lymphocyte functionMetabolomics and systems pharmacology: why and how to model the human metabolic network for drug discoveryM2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation.Free Glycine Accelerates the Autoproteolytic Activation of Human AsparaginaseStructure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDOHeterogeneity of glycolysis in cancers and therapeutic opportunities.Undercover: gene control by metabolites and metabolic enzymesMetabolomic profiling of hormone-dependent cancers: a bird's eye viewMetabolic pathways promoting cancer cell survival and growthStructures of pyruvate kinases display evolutionarily divergent allosteric strategiesMitochondrial dysfunction remodels one-carbon metabolism in human cellsKDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid MetabolismDetection of secondary binding sites in proteins using fragment screeningDirect measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activitymzMatch-ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry dataPyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23Analysis and interpretation of transcriptomic data obtained from extended Warburg effect genes in patients with clear cell renal cell carcinoma.Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites.One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.Human 60-kDa lysophospholipase contains an N-terminal L-asparaginase domain that is allosterically regulated by L-asparagine.Stable isotope-labeling studies in metabolomics: new insights into structure and dynamics of metabolic networks.Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.The early metabolomic response of adipose tissue during acute cold exposure in mice.Quantitative flux analysis reveals folate-dependent NADPH production.Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment.Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MS.Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesisMetabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defensePKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.Role of aerobic glycolysis in genetically engineered mouse models of cancer.Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.
P2860
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P2860
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@ast
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@en
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@nl
type
label
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@ast
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@en
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@nl
prefLabel
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@ast
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@en
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
@en
P2093
Achuthanunni Chokkathukalam
Agnès C L Martin
Andris Jankevics
Barbara Chaneton
Finn P Holding
Joseph E Coyle
Karen H Vousden
Liang Zheng
Marc O'Reilly
P2507
P2860
P2888
P304
P3181
P356
10.1038/NATURE11540
P407
P577
2012-10-14T00:00:00Z
P6179
1000007436