Structural insight into activation mechanism of Toxoplasma gondii nucleoside triphosphate diphosphohydrolases by disulfide reduction
about
The crystal structure of Toxoplasma gondii nucleoside triphosphate diphosphohydrolase 1 represents a conformational intermediate in the reductive activation mechanism of the tetrameric enzymeThe ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate baseStructures of Legionella pneumophila NTPDase1 in complex with polyoxometallatesThe biochemical properties of the Arabidopsis ecto-nucleoside triphosphate diphosphohydrolase AtAPY1 contradict a direct role in purinergic signalingCellular function and molecular structure of ecto-nucleotidases.The tandemly repeated NTPase (NTPDase) from Neospora caninum is a canonical dense granule protein whose RNA expression, protein secretion and phosphorylation coincides with the tachyzoite egress.Screening for small molecule inhibitors of Toxoplasma gondii.Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors.Structures and kinetics for plant nucleoside triphosphate diphosphohydrolases support a domain motion catalytic mechanism.New crystal forms of NTPDase1 from the bacterium Legionella pneumophila
P2860
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P2860
Structural insight into activation mechanism of Toxoplasma gondii nucleoside triphosphate diphosphohydrolases by disulfide reduction
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structural Insight into Activa ...... rolases by Disulfide Reduction
@nl
Structural insight into activa ...... rolases by disulfide reduction
@ast
Structural insight into activa ...... rolases by disulfide reduction
@en
type
label
Structural Insight into Activa ...... rolases by Disulfide Reduction
@nl
Structural insight into activa ...... rolases by disulfide reduction
@ast
Structural insight into activa ...... rolases by disulfide reduction
@en
prefLabel
Structural Insight into Activa ...... rolases by Disulfide Reduction
@nl
Structural insight into activa ...... rolases by disulfide reduction
@ast
Structural insight into activa ...... rolases by disulfide reduction
@en
P2093
P2860
P3181
P356
P1476
Structural insight into activa ...... rolases by disulfide reduction
@en
P2093
Matthias Zebisch
Michel Krauss
Norbert Sträter
Ulrike Krug
P2860
P304
P3181
P356
10.1074/JBC.M111.294348
P407
P577
2011-11-30T00:00:00Z