Full-length Gαq–phospholipase C-β3 structure reveals interfaces of the C-terminal coiled-coil domain
about
Structural and Functional Analysis of the Regulator of G Protein Signaling 2-Gαq ComplexStrike a pose: Gαq complexes at the membraneAn intact helical domain is required for Gα14 to stimulate phospholipase CβPhospholipase Cβ1 induces membrane tubulation and is involved in caveolae formation.M3 muscarinic receptor interaction with phospholipase C β3 determines its signaling efficiency.Membrane-induced allosteric control of phospholipase C-β isozymes.Molecular mechanisms of phospholipase C β3 autoinhibition.Phospholipase C-β in immune cells.PLCβ3 mediates cortactin interaction with WAVE2 in MCP1-induced actin polymerization and cell migrationIntrinsic Pleckstrin Homology (PH) Domain Motion in Phospholipase C-β Exposes a Gβγ Protein Binding Site.Structural insights into phospholipase C-β function.Collective variable approaches for single molecule flexible fitting and enhanced sampling.Structural rearrangements of a polyketide synthase module during its catalytic cycle.Structure of a modular polyketide synthase.Regulation of phospholipase C-β(1) GTPase-activating protein (GAP) function and relationship to G(q) efficacy.Potent and Selective Peptide-based Inhibition of the G Protein Gαq.Cinacalcet corrects hypercalcemia in mice with an inactivating Gα11 mutation.The binding of activated Gαq to phospholipase C-β exhibits anomalous affinity.
P2860
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P2860
Full-length Gαq–phospholipase C-β3 structure reveals interfaces of the C-terminal coiled-coil domain
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@ast
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@en
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@nl
type
label
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@ast
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@en
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@nl
prefLabel
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@ast
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@en
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@nl
P2093
P2860
P356
P1476
Full-length Gαq–phospholipase ...... C-terminal coiled-coil domain
@en
P2093
Angeline M Lyon
Cassandra A Boguth
John J G Tesmer
Somnath Dutta
P2860
P2888
P304
P356
10.1038/NSMB.2497
P577
2013-03-01T00:00:00Z
P5875
P6179
1033407875