Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II - sprookjes - yvandenbroek - TriplyDB

Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

http://www.wikidata.org/entity/Q27676468

about

Activation and allosteric modulation of a muscarinic acetylcholine receptor Engineering therapeutic antibodies targeting G-protein-coupled receptors Large-scale production and protein engineering of G protein-coupled receptors for structural studies Constitutively active rhodopsin and retinal disease Overexpression of membrane proteins in mammalian cells for structural studies Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Insights into congenital stationary night blindness based on the structure of G90D rhodopsin Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gαi1.Opsin, a structural model for olfactory receptors?Structural role of the T94I rhodopsin mutation in congenital stationary night blindness Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors Structural approaches to understanding retinal proteins needed for vision Sequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysis Chemistry and biology of the initial steps in vision: the Friedenwald lecture.Arrestin-Bound Rhodopsin: A Molecular Structure and its Impact on the Development of Biased GPCR Ligands.Vibrational resonance, allostery, and activation in rhodopsin-like G protein-coupled receptors.Structure-function of the G protein-coupled receptor superfamily.Retinal ligand mobility explains internal hydration and reconciles active rhodopsin structures Smoothened goes molecular: new pieces in the hedgehog signaling puzzle Rhodopsin TM6 can interact with two separate and distinct sites on arrestin: evidence for structural plasticity and multiple docking modes in arrestin-rhodopsin binding Engineering cells to improve protein expression.Relocating the active-site lysine in rhodopsin and implications for evolution of retinylidene proteins.Engineering of an artificial light-modulated potassium channel.Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices.Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.High-level expression, purification and characterization of a constitutively active thromboxane A2 receptor polymorphic variant.G protein-coupled receptors--recent advances Conformational selection and equilibrium governs the ability of retinals to bind opsin.Active-state model of a dopamine D2 receptor-Gαi complex stabilized by aripiprazole-type partial agonists.Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein.Allosteric effects of sodium ion binding on activation of the m3 muscarinic g-protein-coupled receptor.Uncovering the triggers for GPCR activation using solid-state NMR spectroscopy.Stabilization of G protein-coupled receptors by point mutations.Buried ionizable networks are an ancient hallmark of G protein-coupled receptor activation Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.Structural dynamics and energetics underlying allosteric inactivation of the cannabinoid receptor CB1.Role of Structural Dynamics at the Receptor G Protein Interface for Signal Transduction Time-resolved structural studies with serial crystallography: A new light on retinal proteins.

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P2860

Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

http://www.wikidata.org/entity/Q27676468

description

2012 nî lūn-bûn

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2012 թվականի հունվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Stabilized G protein binding s ...... tively active metarhodopsin-II

@ast

Stabilized G protein binding s ...... tively active metarhodopsin-II

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Stabilized G protein binding s ...... tively active metarhodopsin-II

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type

label

Stabilized G protein binding s ...... tively active metarhodopsin-II

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Stabilized G protein binding s ...... tively active metarhodopsin-II

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Stabilized G protein binding s ...... tively active metarhodopsin-II

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prefLabel

Stabilized G protein binding s ...... tively active metarhodopsin-II

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Stabilized G protein binding s ...... tively active metarhodopsin-II

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Stabilized G protein binding s ...... tively active metarhodopsin-II

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PNAS.1114089108

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Proceedings of the National Academy of Sciences of the United States of America

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Stabilized G protein binding s ...... tively active metarhodopsin-II

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Ankita Singhal

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Benjamin Nickle

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Daniel Oprian

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Patricia Edwards

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P2860

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

Crystal structure of the β2 adrenergic receptor-Gs protein complex

Crystal structure of rhodopsin: A G protein-coupled receptor

Crystal Structure of a Thermally Stable Rhodopsin Mutant

Crystal structure of the ligand-free G-protein-coupled receptor opsin

Crystal structure of opsin in its G-protein-interacting conformation

Crystal structure of metarhodopsin II

The structural basis of agonist-induced activation in constitutively active rhodopsin

Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness

A ligand channel through the G protein coupled receptor opsin

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435042

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10.1073/PNAS.1114089108

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1

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109

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Jörg Standfuss

Gebhard Schertler

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2012-01-03T00:00:00Z

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51924538

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22198838

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protein structure

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3252945

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