Structural Features for Functional Selectivity at Serotonin Receptors - sprookjes - yvandenbroek - TriplyDB

Structural Features for Functional Selectivity at Serotonin Receptors

Structural Features for Functional Selectivity at Serotonin Receptors

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Classical hallucinogens as antidepressants? A review of pharmacodynamics and putative clinical roles G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRs Structural Studies of G Protein-Coupled Receptors Legal highs: staying on top of the flood of novel psychoactive substances Biased and g protein-independent signaling of chemokine receptors Post-expression strategies for structural investigations of membrane proteins.Large-scale production and protein engineering of G protein-coupled receptors for structural studies DREADDs: novel tools for drug discovery and development Constitutively active rhodopsin and retinal disease Serotonin signaling in Schistosoma mansoni: a serotonin-activated G protein-coupled receptor controls parasite movement Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Structural Basis for Molecular Recognition at Serotonin Receptors Serial Femtosecond Crystallography of G Protein-Coupled Receptors Molecular control of δ-opioid receptor signalling Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs Comprehensive characterization of the Published Kinase Inhibitor Set Full and Partial Agonism of a Designed Enzyme Switch Multiple conformational states in retrospective virtual screening – homology models vs. crystal structures: beta-2 adrenergic receptor case study Membrane-Mediated Oligomerization of G Protein Coupled Receptors and Its Implications for GPCR Function Immunomodulatory effects mediated by serotonin Structural insights into ligand recognition and selectivity for classes A, B, and C GPCRs Larvae of the small white butterfly, Pieris rapae, express a novel serotonin receptor A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2 Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congeners A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity Similarities between the Binding Sites of SB-206553 at Serotonin Type 2 and Alpha7 Acetylcholine Nicotinic Receptors: Rationale for Its Polypharmacological Profile Sequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysis Cholesterol binding to ion channels Topography prediction of helical transmembrane proteins by a new modification of the sliding window method.Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography.The role of experimental and computational structural approaches in 7TM drug discovery.Structure and function of serotonin G protein-coupled receptors.Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR)The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site.Femtosecond crystallography of membrane proteins in the lipidic cubic phase.Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor Global fold of human cannabinoid type 2 receptor probed by solid-state 13C-, 15N-MAS NMR and molecular dynamics simulations.Predictive in silico studies of human 5-hydroxytryptamine receptor subtype 2B (5-HT2B) and valvular heart disease

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Structural Features for Functional Selectivity at Serotonin Receptors

http://www.wikidata.org/entity/Q27676930

description

2013 nî lūn-bûn

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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2013 թվականի մայիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Structural Features for Functional Selectivity at Serotonin Receptors

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Structural Features for Functional Selectivity at Serotonin Receptors

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Structural Features for Functional Selectivity at Serotonin Receptors

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type

label

Structural Features for Functional Selectivity at Serotonin Receptors

@ast

Structural Features for Functional Selectivity at Serotonin Receptors

@en

Structural Features for Functional Selectivity at Serotonin Receptors

@nl

prefLabel

Structural Features for Functional Selectivity at Serotonin Receptors

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Structural Features for Functional Selectivity at Serotonin Receptors

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Structural Features for Functional Selectivity at Serotonin Receptors

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Structural Features for Functional Selectivity at Serotonin Receptors

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Bryan L Roth

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Chong Wang

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Eyal Vardy

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Fai Yiu Siu

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Gye Won Han

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H Eric Xu

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John D McCorvy

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Meihua Chu

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Wei Liu

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Xi-Ping Huang

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P2860

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

Structure of an agonist-bound human A2A adenosine receptor

Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

Crystal structure of the β2 adrenergic receptor-Gs protein complex

PHENIX: a comprehensive Python-based system for macromolecular structure solution

The genetic design of signaling cascades to record receptor activation

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

Redesign of a four-helix bundle protein by phage display coupled with proteolysis and structural characterization by NMR and X-ray crystallography

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340

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Vsevolod Katritch

Raymond C Stevens

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