Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1
about
Antigenic peptide trimming by ER aminopeptidases--insights from structural studiesThe X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide ProcessingERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responsesStructural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing.The Human Leukocyte Antigen (HLA)-B27 Peptidome in Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion.Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines.The Role of Conformational Dynamics in Antigen Trimming by Intracellular Aminopeptidases.Crystal structure of a polypeptide's C-terminus in complex with the regulatory domain of ER aminopeptidase 1.
P2860
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P2860
Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1
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2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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Structural insights into the m ...... reticulum aminopeptidase ERAP1
@ast
Structural insights into the m ...... reticulum aminopeptidase ERAP1
@en
Structural insights into the m ...... reticulum aminopeptidase ERAP1
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label
Structural insights into the m ...... reticulum aminopeptidase ERAP1
@ast
Structural insights into the m ...... reticulum aminopeptidase ERAP1
@en
Structural insights into the m ...... reticulum aminopeptidase ERAP1
@nl
prefLabel
Structural insights into the m ...... reticulum aminopeptidase ERAP1
@ast
Structural insights into the m ...... reticulum aminopeptidase ERAP1
@en
Structural insights into the m ...... reticulum aminopeptidase ERAP1
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structural insights into the m ...... reticulum aminopeptidase ERAP1
@en
P2093
Amit Gandhi
Damodharan Lakshminarasimhan
Hwai-Chen Guo
P2860
P2888
P3181
P356
10.1038/SREP00186
P407
P577
2011-01-01T00:00:00Z
P5875
P6179
1038962405