Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation - sprookjes - yvandenbroek - TriplyDB

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs The CRISPR/Cas Genome-Editing Tool: Application in Improvement of Crops The Rise of CRISPR/Cas for Genome Editing in Stem Cells Genome-editing Technologies for Gene and Cell Therapy Diversity of CRISPR-Cas immune systems and molecular machines Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases Enabling functional genomics with genome engineering Strategies for precision modulation of gene expression by epigenome editing: an overview Designed nucleases for targeted genome editing Use of designer nucleases for targeted gene and genome editing in plants Classification and evolution of type II CRISPR-Cas systems Small RNAs, 5' UTR elements and RNA-binding proteins in intracellular bacteria: impact on metabolism and virulence Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity Off-target Effects in CRISPR/Cas9-mediated Genome Engineering Making designer mutants in model organisms CRISPR-Cas systems: Prokaryotes upgrade to adaptive immunity RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system.Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage The crystal structure of Cpf1 in complex with CRISPR RNA Small Non-Coding RNAs: New Insights in Modulation of Host Immune Response by Intracellular Bacterial Pathogens Survival and Evolution of CRISPR-Cas System in Prokaryotes and Its Applications CRISPR-Cas9: Tool for Qualitative and Quantitative Plant Genome Editing Functional annotation of cis-regulatory elements in human cells by dCas9/sgRNA The CRISPR system can correct or modify the expression of genes responsible for hereditary diseases Development and applications of CRISPR-Cas9 for genome engineering.Genome editing. The new frontier of genome engineering with CRISPR-Cas9 A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation Structure Principles of CRISPR-Cas Surveillance and Effector Complexes Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification Engineering of temperature- and light-switchable Cas9 variants Harnessing CRISPR-Cas9 immunity for genetic engineering A CRISPR toolbox to study virus-host interactions Mutations in Cas9 Enhance the Rate of Acquisition of Viral Spacer Sequences during the CRISPR-Cas Immune Response.Annotation and Classification of CRISPR-Cas Systems.Covalent Modification of Bacteriophage T4 DNA Inhibits CRISPR-Cas9.Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations.

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

http://www.wikidata.org/entity/Q27681624

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2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Anthony T Iavarone

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CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA

Electrostatics of nanosystems: application to microtubules and the ribosome

Cas9 as a versatile tool for engineering biology

RNA-guided human genome engineering via Cas9

CRISPR-based adaptive immune systems

Multiplex genome engineering using CRISPR/Cas systems

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

PHENIX: a comprehensive Python-based system for macromolecular structure solution

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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