Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design
about
Cellular defense against latent colonization foiled by human cytomegalovirus UL138 protein.Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression.CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4.The Role of CtBP1 in Oncogenic Processes and Its Potential as a Therapeutic Target.CtBP- an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors.Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP).Structure-guided design of a high affinity inhibitor to human CtBP.Assembly of human C-terminal Binding Protein (CtBP) into tetramers.Molecular link between glucose and glutamine consumption in cancer cells mediated by CtBP and SIRT4.
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P2860
Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Crystal structures of human Ct ...... es useful for inhibitor design
@ast
Crystal structures of human Ct ...... es useful for inhibitor design
@en
Crystal structures of human Ct ...... es useful for inhibitor design
@nl
type
label
Crystal structures of human Ct ...... es useful for inhibitor design
@ast
Crystal structures of human Ct ...... es useful for inhibitor design
@en
Crystal structures of human Ct ...... es useful for inhibitor design
@nl
prefLabel
Crystal structures of human Ct ...... es useful for inhibitor design
@ast
Crystal structures of human Ct ...... es useful for inhibitor design
@en
Crystal structures of human Ct ...... es useful for inhibitor design
@nl
P2093
P2860
P921
P1433
P1476
Crystal structures of human Ct ...... es useful for inhibitor design
@en
P2093
Brendan J Hilbert
Celia A Schiffer
Steven R Grossman
William E Royer
P2860
P304
P356
10.1016/J.FEBSLET.2014.03.026
P407
P577
2014-05-02T00:00:00Z