Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism
about
Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension.Crystallographic analysis of the laminin β2 short arm reveals how the LF domain is inserted into a regular array of LE domainsInformation processing in the CNS: a supramolecular chemistry?NOVA2-mediated RNA regulation is required for axonal pathfinding during developmentStructural decoding of netrin-4 reveals a regulatory function towards mature basement membranesRecurrent DCC gene losses during bird evolutionAnchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer)CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development.Milk fat globule-EGF factor VIII attenuates CNS injury by promoting neural stem cell proliferation and migration after cerebral ischemiaNetrin-5 is highly expressed in neurogenic regions of the adult brain.Glypican Is a Modulator of Netrin-Mediated Axon GuidanceNetrin-1 directs dendritic growth and connectivity of vertebrate central neurons in vivo.Signaling mechanism of the netrin-1 receptor DCC in axon guidance.Netrin1-DCC-Mediated Attraction Guides Post-Crossing Commissural Axons in the HindbrainReconstruction of Multiple Facial Nerve Branches Using Skeletal Muscle-Derived Multipotent Stem Cell Sheet-Pellet Transplantation.Netrin-1 Reduces Monocyte and Macrophage Chemotaxis towards the Complement Component C5a.Phenotypic analysis of mice completely lacking netrin 1.Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex.Floor plate-derived neuropilin-2 functions as a secreted semaphorin sink to facilitate commissural axon midline crossing.Netrin-1-Regulated Distribution of UNC5B and DCC in Live Cells Revealed by TICCS.NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord.Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord.Evolution of the functionally conserved DCC gene in birdsNetrin-1 acts as a non-canonical angiogenic factor produced by human Wharton's jelly mesenchymal stem cells (WJ-MSC).Role of Netrin-1 Signaling in Nerve Regeneration.The Neural Stem Cell Microenvironment: Focusing on Axon Guidance Molecules and Myelin-Associated Factors.Crossing the embryonic midline: molecular mechanisms regulating axon responsiveness at an intermediate target.Attractive and repulsive factors act through multi-subunit receptor complexes to regulate nerve fiber growth.Releasing 'brakes' to nerve regeneration: intrinsic molecular targets.Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.Gametophytic Pollen Tube Guidance: Attractant Peptides, Gametic Controls, and Receptors.Neurogenesis: Regulation by Alternative Splicing and Related Posttranscriptional Processes.Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC.Netrin-1 Derived from the Ventricular Zone, but not the Floor Plate, Directs Hindbrain Commissural Axons to the Ventral Midline.Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance.Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness.DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development.DCC mutation update: Congenital mirror movements, isolated agenesis of the corpus callosum, and developmental split brain syndrome.Regeneration of sciatic nerve crush injury by a hydroxyapatite nanoparticle-containing collagen type I hydrogel.
P2860
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P2860
Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@ast
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@en
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@nl
type
label
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@ast
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@en
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@nl
prefLabel
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@ast
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@en
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Structures of netrin-1 bound t ...... to its axon guidance mechanism
@en
P2093
Alexander Antipenko
Dimitar B Nikolov
Dorothea Tzvetkova-Robev
Juha Himanen
Kanagalaghatta R Rajashankar
Maria Minchenko
Vincenzo Nardi-Dei
P2860
P304
P3181
P356
10.1126/SCIENCE.1255149
P407
P577
2014-06-13T00:00:00Z