Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs

Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs

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http://www.wikidata.org/entity/Q27684540
The genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene familiesTrehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in MiceEnzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatasesPanoramic view of a superfamily of phosphatases through substrate profilingStructures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysisTrehalose pathway as an antifungal target.Central Role of the Trehalose Biosynthesis Pathway in the Pathogenesis of Human Fungal Infections: Opportunities and Challenges for Therapeutic Development.Expression of Genes Encoding the Enzymes for Glycogen and Trehalose Metabolism in L3 and L4 Larvae of Anisakis simplex.Investigating trehalose synthesis genes after cold acclimation in the Antarctic nematode Panagrolaimus sp. DAW1.The in vitro effect of ivermectin on the activity of trehalose synthesis pathway enzymes and their mRNA expression in the muscle of adult female Ascaris suum (Nematoda).Trehalose-6-phosphate phosphatase as a broad-spectrum therapeutic target against eukaryotic and prokaryotic pathogens
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Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs

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http://www.wikidata.org/entity/Q27684540
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the trehalose-6-p ...... nciples for anthelmintic drugs
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Structure of the Trehalose-6-p ...... nciples for Anthelmintic Drugs
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10.1371/JOURNAL.PPAT.1004245
P407
P433
P478
P50
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P5875
P698
P921
P932