Structural basis for sialic acid-mediated self-recognition by complement factor H - sprookjes - yvandenbroek - TriplyDB

Structural basis for sialic acid-mediated self-recognition by complement factor H

Structural basis for sialic acid-mediated self-recognition by complement factor H

http://www.wikidata.org/entity/Q27696183

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"Rules of Engagement" of Protein-Glycoconjugate Interactions: A Molecular View Achievable by using NMR Spectroscopy and Molecular Modeling Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous Nephropathy Complement Factor H and Simian Virus 40 bind the GM1 ganglioside in distinct conformations Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome.The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease.Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases.A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.Self-nonself discrimination by the complement system.Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion Factor H Family Proteins in Complement Evasion of Microorganisms.Complement System Part I - Molecular Mechanisms of Activation and Regulation.Structural and Functional Analysis of Murine Polyomavirus Capsid Proteins Establish the Determinants of Ligand Recognition and Pathogenicity.Utilizing CMP-Sialic Acid Analogs to Unravel Neisseria gonorrhoeae Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics.Desialylation of Spermatozoa and Epithelial Cell Glycocalyx Is a Consequence of Bacterial Infection of the Epididymis.Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions.Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry.Complement activation, regulation, and molecular basis for complement-related diseases Anti-complement activity of the Ixodes scapularis salivary protein Salp20.Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation.Annexin A2 Enhances Complement Activation by Inhibiting Factor H A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae.Selectivity of C3-opsonin targeted complement inhibitors: A distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients.Insights into the Effects of Complement Factor H on the Assembly and Decay of the Alternative Pathway C3 Proconvertase and C3 Convertase.Defining the Binding Region in Factor H to Develop a Therapeutic Factor H-Fc Fusion Protein against Non-Typeable Haemophilus influenzae Precision glycocalyx editing as a strategy for cancer immunotherapy.Analysis of Linear Antibody Epitopes on Factor H and CFHR1 Using Sera of Patients with Autoimmune Atypical Hemolytic Uremic Syndrome.Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation Structural insights on complement activation.How novel structures inform understanding of complement function.Liquid chromatography-tandem mass spectrometry-based fragmentation analysis of glycopeptides.Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: Lessons from the pathogenic Neisseriae.Biological roles of glycans.Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation.Protection of host cells by complement regulators.Endothelial cells: source, barrier, and target of defensive mediators.Complement factor H in host defense and immune evasion.Complementopathies.The bittersweet taste of tubulo-interstitial glycans.Discovery and characterization of de novo sialic acid biosynthesis in the phylum Fusobacterium.

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Structural basis for sialic acid-mediated self-recognition by complement factor H

http://www.wikidata.org/entity/Q27696183

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2015 թվականի հունվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Structural basis for sialic acid-mediated self-recognition by complement factor H

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Nature Chemical Biology

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Structural basis for sialic acid-mediated self-recognition by complement factor H

@en

P2093

Andrew P Herbert

http://www.w3.org/2001/XMLSchema#string

Bärbel S Blaum

http://www.w3.org/2001/XMLSchema#string

Dušan Uhrín

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N.m.r. and molecular-modelling studies of the solution conformation of heparin

Structural basis for engagement by complement factor H of C3b on a self surface

Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement

The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module

Structural implications of Siglec-5-mediated sialoglycan recognition

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Structural basis for complement factor H linked age-related macular degeneration

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

Siglecs as sensors of self in innate and adaptive immune responses

Complement factor H related proteins (CFHRs)

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77-82

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scholarly article

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2104835

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10.1038/NCHEMBIO.1696

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1

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11

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Jonathan P Hannan

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2015-01-01T00:00:00Z

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268450194

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1043983949

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25402769

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