Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
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The Intracellular Loop of the Glycine Receptor: It's not all about the SizeX-ray structure of the human α4β2 nicotinic receptorSignal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion ChannelsFunctional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor HomologuesMurine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.Identification of a pre-active conformation of a pentameric channel receptorKorean Variant Archive (KOVA): a reference database of genetic variations in the Korean population.Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor.Functional modulation of glycine receptors by the alkaloid gelsemine.Tuning the ion selectivity of glutamate transporter-associated uncoupled conductancesIdentification of an Inhibitory Alcohol Binding Site in GABAA ρ1 ReceptorsFunctional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel.Competitive antagonists facilitate the recovery from desensitization of α1β2γ2 GABAA receptors expressed in Xenopus oocytesCrystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamerAllosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazineFunctional Annotation of Ion Channel Structures by Molecular Simulation.Structural Studies of Nicotinic Acetylcholine Receptors: Using Acetylcholine-Binding Protein as a Structural Surrogate.Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease.Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor.Regulation of neuronal chloride homeostasis by neuromodulators.Understanding structure-function relationships of the human neuronal acetylcholine receptor: insights from the first crystal structures of neuronal subunits.Structural mechanisms of activation and desensitization in neurotransmitter-gated ion channels.Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.Architecture and functional properties of the CFTR channel pore.Nicotinic acetylcholine receptors at the single-channel level.Structural Studies of GABAA Receptor Binding Sites: Which Experimental Structure Tells us What?Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from Escherichia coli.Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbersDisturbances of Ligand Potency and Enhanced Degradation of the Human Glycine Receptor at Affected Positions G160 and T162 Originally Identified in Patients Suffering from Hyperekplexia.The GlyR Extracellular β8-β9 Loop - A Functional Determinant of Agonist Potency.String method solution of the gating pathways for a pentameric ligand-gated ion channel.Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators.Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors.A Continuum Poisson-Boltzmann Model for Membrane Channel Proteins.Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics.Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites.Structural basis for GABAA receptor potentiation by neurosteroids.Side chain flexibility and the pore dimensions in the GABAA receptor.The role of charged residues in independent glycine receptor folding domains for intermolecular interactions and ion channel function.
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P2860
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
description
2015 nî lūn-bûn
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2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@ast
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@en
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@nl
type
label
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@ast
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@en
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@nl
prefLabel
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@ast
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@en
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@nl
P2093
P2860
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P1476
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
@en
P2093
Klaus Michelsen
Paul L Shaffer
Stephen Schneider
P2860
P2888
P304
P3181
P356
10.1038/NATURE14972
P407
P577
2015-10-08T00:00:00Z
P6179
1016019335