Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin
about
Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplexChiral discrimination in platinum anticancer drugs.The path for metal complexes to a DNA targetStrategies to target tumors using nanodelivery systems based on biodegradable polymers, aspects of intellectual property, and marketDendrimers bind antioxidant polyphenols and cisplatin drugCrystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated siteA crystallographic map of the transition from B-DNA to A-DNA.2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplexStructure and dynamics of thioguanine-modified duplex DNAStructural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4Structure of duplex DNA containing the cisplatin 1,2-{Pt(NH3)2}2+-d(GpG) cross-link at 1.77Å resolutionStructural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNAInteraction of FACT, SSRP1, and the high mobility group (HMG) domain of SSRP1 with DNA damaged by the anticancer drug cisplatinIdentification of cisplatin-binding proteins using agarose conjugates of platinum compoundsAnalysis of structural flexibility of damaged DNA using thiol-tethered oligonucleotide duplexesATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosisRevealing Three Stages of DNA-Cisplatin Reaction by a Solid-State NanoporeReplication protein A (RPA) binding to duplex cisplatin-damaged DNA is mediated through the generation of single-stranded DNA.Stopped-flow kinetic analysis of replication protein A-binding DNA: damage recognition and affinity for single-stranded DNA reveal differential contributions of k(on) and k(off) rate constants.Double-check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair.DNA oligonucleotide duplexes containing intramolecular platinated cross-links: energetics, hydration, sequence, and ionic effects.Cisplatin adducts of d(CCTCTG*G*TCTCC).d(GGAGACCAGAGG) in aqueous solution by vibrational circular dichroism spectroscopy.A monofunctional platinum complex coordinated to a rhodium metalloinsertor selectively binds mismatched DNA in the minor groove.Targeting DNA Mismatches with Rhodium Metalloinsertors.Study of the interaction of DNA with cisplatin and other Pd(II) and Pt(II) complexes by atomic force microscopy.Gas-phase ion/ion reactions of transition metal complex cations with multiply charged oligodeoxynucleotide anions.Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer.Towards Antitumor Active trans-Platinum Compounds.The major chromatin protein histone H1 binds preferentially to cis-platinum-damaged DNASynergistic antitumor effect of AAV-mediated TRAIL expression combined with cisplatin on head and neck squamous cell carcinomaUnusual DNA binding modes for metal anticancer complexes.Intrinsic conformational energetics associated with the glycosyl torsion in DNA: a quantum mechanical study.Sequence-dependent dynamics of duplex DNA: the applicability of a dinucleotide modelThermodynamic and hydration effects for the incorporation of a cationic 3-aminopropyl chain into DNAGenomics, complexity and drug discovery: insights from Boolean network models of cellular regulation.Understanding and improving platinum anticancer drugs--phenanthriplatinHerpes simplex virus type-1 single-strand DNA-binding protein (ICP8) enhances the ability of the viral DNA helicase-primase to unwind cisplatin-modified DNA.The phosphate clamp: a small and independent motif for nucleic acid backbone recognitionExcursions in polynuclear platinum DNA binding.
P2860
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P2860
Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Crystal structure of double-st ...... the anticancer drug cisplatin
@ast
Crystal structure of double-st ...... the anticancer drug cisplatin
@en
Crystal structure of double-st ...... the anticancer drug cisplatin
@nl
type
label
Crystal structure of double-st ...... the anticancer drug cisplatin
@ast
Crystal structure of double-st ...... the anticancer drug cisplatin
@en
Crystal structure of double-st ...... the anticancer drug cisplatin
@nl
prefLabel
Crystal structure of double-st ...... the anticancer drug cisplatin
@ast
Crystal structure of double-st ...... the anticancer drug cisplatin
@en
Crystal structure of double-st ...... the anticancer drug cisplatin
@nl
P2093
P3181
P356
P1433
P1476
Crystal structure of double-st ...... the anticancer drug cisplatin
@en
P2093
A C Rosenzweig
C A Frederick
P M Takahara
S J Lippard
P2888
P304
P3181
P356
10.1038/377649A0
P407
P577
1995-10-19T00:00:00Z
P6179
1027650694