Crystal structure of a catalytic antibody with a serine protease active site
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Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolutionA Drosophila pattern recognition receptor contains a peptidoglycan docking groove and unusual L,D-carboxypeptidase activityStructural and functional characterization of a monoclonal antibody specific for the preS1 region of hepatitis B virusCrystal structure of the complex of a catalytic antibody Fab fragment with a transition state analog: structural similarities in esterase-like catalytic antibodiesCrystal structure of varicella-zoster virus proteaseX-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product releaseCrystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzymeStructural basis of substrate specificity in the serine proteasesCharacterizing the microenvironment surrounding protein sites.Routes to covalent catalysis by reactive selection for nascent protein nucleophilesStructural and energetic determinants of the S1-site specificity in serine proteases.Enzyme mimicry by the antiidiotypic antibody approach.Mechanistically different catalytic antibodies obtained from immunization with a single transition-state analogPhage display of a catalytic antibody to optimize affinity for transition-state analog binding.A Monoclonal Antibody to Cryptococcus neoformans Glucuronoxylomannan Manifests Hydrolytic Activity for Both Peptides and Polysaccharides.Antibody-Mediated Catalysis in Infection and Immunity.Modifications to canonical structure sequence patterns: analysis for L1 and L3.Catalytic antibodies--reaching adolescence?Canonical structures of short CDR-L3 in antibodiesLosac, the first hemolin that exhibits procogulant activity through selective factor X proteolytic activation.Characterization of the hydrolytic activity of a polyclonal catalytic antibody preparation by pH-dependence and chemical modification studies: evidence for the involvement of Tyr and Arg side chains as hydrogen-bond donors.Tailoring the pH dependence of human non-pancreatic secretory phospholipase A2 by engineering surface charges.Intrabody construction and expression III: engineering hyperstable V(H) domains.Phosphonate ester probes for proteolytic antibodies.Transition state docking: a probe for noncovalent catalysis in biological systems. Application to antibody-catalyzed ester hydrolysis.Specific HIV gp120-cleaving antibodies induced by covalently reactive analog of gp120.Towards covalent vaccination: improved polyclonal HIV neutralizing antibody response induced by an electrophilic gp120 V3 peptide analog.Enzyme-catalyzed synthesis of isosteric phosphono-analogues of sugar nucleotides.Binding and catalysis: a thermodynamic study on a catalytic antibody system.Broadly distributed chemical reactivity of natural antibodies expressed in coordination with specific antigen binding activity.Crystal structure of a rhomboid family intramembrane protease.The functional architecture of an acetylcholine receptor-mimicking antibody.Purification and characterization of a specific late-larval esterase from two species of the Drosophila repleta group: contributions to understand its evolution
P2860
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P2860
Crystal structure of a catalytic antibody with a serine protease active site
description
1994 nî lūn-bûn
@nan
1994 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Crystal structure of a catalytic antibody with a serine protease active site
@ast
Crystal structure of a catalytic antibody with a serine protease active site
@en
Crystal structure of a catalytic antibody with a serine protease active site
@nl
type
label
Crystal structure of a catalytic antibody with a serine protease active site
@ast
Crystal structure of a catalytic antibody with a serine protease active site
@en
Crystal structure of a catalytic antibody with a serine protease active site
@nl
prefLabel
Crystal structure of a catalytic antibody with a serine protease active site
@ast
Crystal structure of a catalytic antibody with a serine protease active site
@en
Crystal structure of a catalytic antibody with a serine protease active site
@nl
P2093
P921
P356
P1433
P1476
Crystal structure of a catalytic antibody with a serine protease active site
@en
P2093
P304
P356
10.1126/SCIENCE.8066444
P407
P577
1994-08-19T00:00:00Z