Structures of zinc finger domains from transcription factor Sp1. Insights into sequence-specific protein-DNA recognition
about
Genomic structure and cloning of two transcript isoforms of human Sp8Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cellsToward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequencesSp1- and Krüppel-like transcription factorsProtein design: toward functional metalloenzymesCCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactionsThe Role of the Ubiquitously Expressed Transcription Factor Sp1 in Tissue-specific Transcriptional Regulation and in DiseaseDevelopment of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factorsEAPII interacts with ETS1 and modulates its transcriptional functionIn vitro analysis of the zinc-finger motif in human replication protein AZinc finger of replication protein A, a non-DNA binding element, regulates its DNA binding activity through redox.SP1 enhances Zbtb7A gene expression via direct binding to GC box in HePG2 cellsPromiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viabilityZinc finger transcription factor Zn3-Sp1 reactions with Cd2+.Cadmium down-regulation of kidney Sp1 binding to mouse SGLT1 and SGLT2 gene promoters: possible reaction of cadmium with the zinc finger domain of Sp1Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response.miR-365, a novel negative regulator of interleukin-6 gene expression, is cooperatively regulated by Sp1 and NF-kappaB.Interprotein metal exchange between transcription factor IIIa and apo-metallothionein.Zn-, Cd-, and Pb-transcription factor IIIA: properties, DNA binding, and comparison with TFIIIA-finger 3 metal complexesElectrophoretic mobility shift assay of zinc finger proteins: competition for Zn(2+) bound to Sp1 in protocols including EDTA.Transforming growth factor-β-inducible early response gene 1 is a novel substrate for atypical protein kinase Cs.Analysis of the AHR gene proximal promoter GGGGC-repeat polymorphism in lung, breast, and colon cancerIdentification of Critical Elements for Regulation of Inorganic Pyrophosphatase (PPA1) in MCF7 Breast Cancer Cells.Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinologyDNA Methylation Affects the SP1-regulated Transcription of FOXF2 in Breast Cancer Cells.The p16-specific reactivation and inhibition of cell migration through demethylation of CpG islands by engineered transcription factors.Transcription Factor Sp1 Promotes the Expression of Porcine ROCK1 Gene.The interaction between human papillomavirus type 16 and FADD is mediated by a novel E6 binding domain.Evaluation of novel design strategies for developing zinc finger nucleases tools for treating human diseases.Mammalian metallothionein in toxicology, cancer, and cancer chemotherapy.Sp1 and the 'hallmarks of cancer'.Key residues characteristic of GATA N-fingers are recognized by FOG.Mechanism for basal expression of rat mitochondrial branched-chain-2-oxo-acid dehydrogenase kinase [corrected].Lead neurotoxicity: exploring the potential impact of lead substitution in zinc-finger proteins on mental health.N-heterocyclic carbene complexes of silver and gold as novel tools against breast cancer progression.Novel derivative of benzofuran induces cell death mostly by G2/M cell cycle arrest through p53-dependent pathway but partially by inhibition of NF-kappaB.The critical role of the cellular thiol homeostasis in cadmium perturbation of the lung extracellular matrixAltered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the beta-globin locus control region in vivo.Tumor-suppressing effects of microRNA-429 in human renal cell carcinoma via the downregulation of Sp1.Stability and folding behavior analysis of zinc-finger using simple models.
P2860
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P2860
Structures of zinc finger domains from transcription factor Sp1. Insights into sequence-specific protein-DNA recognition
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Structures of zinc finger doma ...... ecific protein-DNA recognition
@ast
Structures of zinc finger doma ...... ecific protein-DNA recognition
@en
Structures of zinc finger doma ...... ecific protein-DNA recognition
@nl
type
label
Structures of zinc finger doma ...... ecific protein-DNA recognition
@ast
Structures of zinc finger doma ...... ecific protein-DNA recognition
@en
Structures of zinc finger doma ...... ecific protein-DNA recognition
@nl
prefLabel
Structures of zinc finger doma ...... ecific protein-DNA recognition
@ast
Structures of zinc finger doma ...... ecific protein-DNA recognition
@en
Structures of zinc finger doma ...... ecific protein-DNA recognition
@nl
P2093
P2860
P356
P1476
Structures of zinc finger doma ...... ecific protein-DNA recognition
@en
P2093
J P Caradonna
R W Kriwacki
V A Narayan
P2860
P304
P356
10.1074/JBC.272.12.7801
P407
P577
1997-03-21T00:00:00Z