The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
about
Stabilization and characterization of a heme-oxy reaction intermediate in inducible nitric-oxide synthaseSubstrate-assisted catalysis: molecular basis and biological significanceProton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymesAllosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistryUnusual oxidative chemistry of N(omega)-hydroxyarginine and N-hydroxyguanidine catalyzed at an engineered cavity in a heme peroxidaseStructural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterinStructural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoformsAnchored plasticity opens doors for selective inhibitor design in nitric oxide synthaseNitric-oxide Synthase Forms N-NO-pterin and S-NO-Cys: IMPLICATIONS FOR ACTIVITY, ALLOSTERY, AND REGULATIONSculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2The structural basis for substrate versatility of chloramphenicol acetyltransferase CATICommunication between the Zinc and Tetrahydrobiopterin Binding Sites in Nitric Oxide SynthaseNitric oxide synthases: structure, function and inhibitionVariations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamilyKinetics of CO binding to the haem domain of murine inducible nitric oxide synthase: differential effects of haem domain ligandsTwo heme-binding domains of heme-regulated eukaryotic initiation factor-2alpha kinase. N terminus and kinase insertionMonomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytesProbing heme coordination states of inducible nitric oxide synthase with a ReI(imidazole-alkyl-nitroarginine) sensitizer-wireCaveolin-1: An Oxidative Stress-Related Target for Cancer Prevention.Dynamin 3 suppresses growth and induces apoptosis of hepatocellular carcinoma cells by activating inducible nitric oxide synthase productionEndothelial nitric oxide in humans in health and disease.Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain.Characterization of key residues in the subdomain encoded by exons 8 and 9 of human inducible nitric oxide synthase: a critical role for Asp-280 in substrate binding and subunit interactions.Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain.Molecular replacement with a large number of molecules in the asymmetric unitOxygen reduction by nitric-oxide synthases.Mechanism of Nitric Oxide Synthase Regulation: Electron Transfer and Interdomain Interactions.Holoenzyme structures of endothelial nitric oxide synthase - an allosteric role for calmodulin in pivoting the FMN domain for electron transferThe structural biochemistry of the superoxide dismutases.Dissecting structural and electronic effects in inducible nitric oxide synthasePulsed ENDOR determination of relative orientation of g-frame and molecular frame of imidazole-coordinated heme center of iNOSInfluence of heme-thiolate in shaping the catalytic properties of a bacterial nitric-oxide synthase.Arg375 tunes tetrahydrobiopterin functions and modulates catalysis by inducible nitric oxide synthaseDeveloping master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.Nitric oxide in liver diseases.Pulsed ENDOR determination of the arginine location in the ferrous-NO form of neuronal NOS.Effects of transition metals on nitric oxide synthase catalysisCloning and characterization of human inducible nitric oxide synthase splice variants: a domain, encoded by exons 8 and 9, is critical for dimerizationTarget- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbersConformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors
P2860
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P2860
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@ast
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@en
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@nl
type
label
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@ast
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@en
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@nl
prefLabel
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@ast
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@en
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@nl
P2093
P1433
P1476
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
@en
P2093
D J Stuehr
E D Getzoff
P304
P356
10.1126/SCIENCE.278.5337.425
P407
P577
1997-10-01T00:00:00Z