Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling
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Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoterSmad proteins function as co-modulators for MEF2 transcriptional regulatory proteinsThe MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoterNuclear targeting of transforming growth factor-beta-activated Smad complexesA novel E1A-like inhibitor of differentiation (EID) family member, EID-2, suppresses transforming growth factor (TGF)-beta signaling by blocking TGF-beta-induced formation of Smad3-Smad4 complexesFeatures of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA bindingSmad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formationRegulation of Hex gene expression by a Smads-dependent signaling pathwayStoichiometry of active smad-transcription factor complexes on DNALigand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signalingA kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genomeRepression of Smad2 and Smad3 transactivating activity by association with a novel splice variant of CCAAT-binding factor C subunitRequirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.Bone morphogenetic protein-4-induced activation of Xretpos is mediated by Smads and Olf-1/EBF associated zinc finger (OAZ).Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytesInactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase IIThe Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signalingTransforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding elementSpecificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteinsOpposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathwayGATA- and Smad1-dependent enhancers in the Smad7 gene differentially interpret bone morphogenetic protein concentrationsAxin and GSK3- control Smad3 protein stability and modulate TGF- signalingThe SmadsCharacterization of a novel transcriptionally active domain in the transforming growth factor beta-regulated Smad3 proteinAn Oct-1 binding site mediates activation of the gata2 promoter by BMP signalingThe Tgif2 gene contains a retained intron within the coding sequence.A Tale from TGF-β Superfamily for Thymus Ontogeny and FunctionTransforming growth factor β signaling in uterine development and functionStructure ofDrosophilaMad MH2 domainStructure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF- effectorsA Smad action turnover switch operated by WW domain readers of a phosphoserine codeTGF-β1/Smads and miR-21 in Renal Fibrosis and InflammationTGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisSmad6 as a transcriptional corepressorThe interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIFSp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cellsIdentification of three novel Smad binding proteins involved in cell polarityBoth Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional activityLefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptorCrossing Smads
P2860
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P2860
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@ast
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@en
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@nl
type
label
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@ast
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@en
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@nl
prefLabel
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@ast
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@en
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@nl
P2093
P3181
P1433
P1476
Crystal structure of a Smad MH ...... binding in TGF-beta signaling
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(00)81600-1
P407
P577
1998-09-04T00:00:00Z