The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
about
Cerebral hemodynamics of the aging brain: risk of Alzheimer disease and benefit of aerobic exerciseInteractions of AChE with Aβ Aggregates in Alzheimer's Brain: Therapeutic Relevance of IDN 5706Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activationMemantine inhibits α3β2-nAChRs-mediated nitrergic neurogenic vasodilation in porcine basilar arteriesOrally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal modelsAlzheimer's disease amyloid-beta links lens and brain pathology in Down syndromeAbeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in DrosophilaTransthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?Recent developments in Alzheimer's disease therapeuticsOrigins of amyloid-βbeta-Amyloid degradation and Alzheimer's diseaseIntracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study.In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques.Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregationClinical immunologic approaches for the treatment of Alzheimer's diseaseImmunotherapy as treatment for Alzheimer’s diseaseThe endocannabinoid system in normal and pathological brain ageingApolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's diseaseAPP binds DR6 to trigger axon pruning and neuron death via distinct caspasesCellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomersAlzheimer's disease as homeostatic responses to age-related myelin breakdownCerebrospinal fluid biomarkers of Alzheimer’s diseaseLatrepirdine for Alzheimer's diseaseStatins for the treatment of dementiaPassive immunisation with monoclonal anti-Abeta antibodies for the treatment of Alzheimer's diseaseDimebon for Alzheimer's diseaseStatins for the treatment of dementiaPrenatal lead levels, plasma amyloid β levels, and gene expression in young adulthoodThe coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathwayArc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generationNeurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratioA genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer diseaseAATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4Effect of N-homocysteinylation on physicochemical and cytotoxic properties of amyloid β-peptideThe role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo.Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's diseaseAmyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS developmentCaspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's diseaseCharacterizing affinity epitopes between prion protein and β-amyloid using an epitope mapping immunoassayInteraction between soluble Aβ-(1-40) monomer and Aβ-(1-42) fibrils probed by paramagnetic relaxation enhancement
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P2860
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@ast
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@en
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@nl
type
label
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@ast
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@en
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@nl
prefLabel
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@ast
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@en
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@nl
P3181
P356
P1433
P1476
The amyloid hypothesis of Alzh ...... ms on the road to therapeutics
@en
P2093
Dennis J Selkoe
P3181
P356
10.1126/SCIENCE.1072994
P407
P577
2002-07-19T00:00:00Z