The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. - sprookjes - yvandenbroek - TriplyDB

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

http://www.wikidata.org/entity/Q27863647

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Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells Identification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeats ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling Smad3 prevents beta-catenin degradation and facilitates beta-catenin nuclear translocation in chondrocytes Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin.Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease The beta-catenin binding protein ICAT modulates androgen receptor activity Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha Wnt/beta-catenin signaling and small molecule inhibitors Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1 Role of the F-box protein Skp2 in lymphomagenesis The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer Amyloid precursor protein modulates beta-catenin degradation Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex Silencing of both beta-TrCP1 and HOS (beta-TrCP2) is required to suppress human immunodeficiency virus type 1 Vpu-mediated CD4 down-modulation Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression Elevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitro The role of the ubiquitination-proteasome pathway in breast cancer: use of mouse models for analyzing ubiquitination processes A protein knockdown strategy to study the function of beta-catenin in tumorigenesis Analysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissues The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications Cullin family proteins and tumorigenesis: genetic association and molecular mechanisms Arginine methyltransferases as novel therapeutic targets for breast cancer BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.Covalent modification of all members of human cullin family proteins by NEDD8 The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4 Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination

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The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

http://www.wikidata.org/entity/Q27863647

description

1999 nî lūn-bûn

@nan

1999 թուականի Յունուարին հրատարակուած գիտական յօդուած

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1999 թվականի հունվարին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin

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prefLabel

The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin.

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The human F box protein beta-T ...... the stability of beta-catenin

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Chiaur DS

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P2860

Association of the APC gene product with beta-catenin

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

Association of the APC tumor suppressor protein with catenins

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

Functional interaction of beta-catenin with the transcription factor LEF-1

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts.

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849-854

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scholarly article

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4292901

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10.1038/SJ.ONC.1202653

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4

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18

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13265172

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1011328429

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10023660

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