The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation.
about
A membrane protein required for dislocation of misfolded proteins from the ERFunction of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chainsCaveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complexDirect binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation.Inhibition of p97-dependent protein degradation by Eeyarestatin IUnsaturated fatty acids inhibit proteasomal degradation of Insig-1 at a postubiquitination stepDetailed structural insights into the p97-Npl4-Ufd1 interfaceDoa1 is a Cdc48 adapter that possesses a novel ubiquitin binding domainProtein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length.The yeast integral membrane protein Apq12 potentially links membrane dynamics to assembly of nuclear pore complexesThe AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol.Sel1p/Ubx2p participates in a distinct Cdc48p-dependent endoplasmic reticulum-associated degradation pathway.The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae.Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase.Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.Physical and genetic associations of the Irc20 ubiquitin ligase with Cdc48 and SUMO.A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathwayHRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins.BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasomeATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activityAAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradationCharacterization of chemically induced liver injuries using gene co-expression modulesTranscriptome Profile of the Response of Paracoccidioides spp. to a Camphene Thiosemicarbazide DerivativePlant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48.A Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.Delivery of ubiquitinated substrates to protein-unfolding machines.The nuclear envelope: filling in gaps.Endoplasmic reticulum-associated degradation is required for cold adaptation and regulation of sterol biosynthesis in the yeast Saccharomyces cerevisiaeUbiquitin-dependent protein degradation at the yeast endoplasmic reticulum and nuclear envelope.Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation.Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97.Ub on the move.Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission.Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocationSearch and destroy: ER quality control and ER-associated protein degradation.Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond.Cellular response to endoplasmic reticulum stress: a matter of life or death.The endoplasmic reticulum-associated degradation pathways of budding yeast.
P2860
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P2860
The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The conserved npl4 protein com ...... anscription factor activation.
@ast
The conserved npl4 protein com ...... anscription factor activation.
@en
The conserved npl4 protein com ...... anscription factor activation.
@nl
type
label
The conserved npl4 protein com ...... anscription factor activation.
@ast
The conserved npl4 protein com ...... anscription factor activation.
@en
The conserved npl4 protein com ...... anscription factor activation.
@nl
prefLabel
The conserved npl4 protein com ...... anscription factor activation.
@ast
The conserved npl4 protein com ...... anscription factor activation.
@en
The conserved npl4 protein com ...... anscription factor activation.
@nl
P2093
P2860
P356
P1476
The conserved npl4 protein com ...... anscription factor activation.
@en
P2093
P2860
P304
P356
10.1091/MBC.12.10.3226
P407
P577
2001-10-01T00:00:00Z