Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
about
HRad17 colocalizes with NHP2L1 in the nucleolus and redistributes after UV irradiationHuman RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta.Nuclear structure in normal and Bloom syndrome cellsBloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseasesNucleolar localization of the Werner syndrome protein in human cellsRequirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiaeMultiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiaeMus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cellsYeast as a model organismComparative genomics and molecular dynamics of DNA repeats in eukaryotesDomain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ familyHuman premature aging, DNA repair and RecQ helicasesMus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiaeEvidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.Sirtuin 1 and sirtuin 3: physiological modulators of metabolismHeterochromatin formation promotes longevity and represses ribosomal RNA synthesisThe Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs.Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatinMutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae.Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing.Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels.Rtg2 protein links metabolism and genome stability in yeast longevityMutations in DNA replication genes reduce yeast life span.Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae.A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair.Sip2p and its partner snf1p kinase affect aging in S. cerevisiae.Constitutive heterochromatin formation and transcription in mammalsThe Bloom's syndrome gene product interacts with topoisomerase IIIDeletion of Ku86 causes early onset of senescence in miceSubstrate-specific inhibition of RecQ helicaseGrowth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocationsA deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacitySirtuins in mammals: insights into their biological functionThe Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity.The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci.Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.Biochemical characterization of the DNA helicase activity of the escherichia coli RecQ helicase.Effects of mutations in SGS1 and in genes functionally related to SGS1 on inverted repeat-stimulated spontaneous unequal sister-chromatid exchange in yeastSmc5/6 maintains stalled replication forks in a recombination-competent conformation.
P2860
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P2860
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@ast
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@en
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@nl
type
label
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@ast
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@en
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@nl
prefLabel
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@ast
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@en
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@nl
P2093
P3181
P1433
P1476
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants.
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.277.5330.1313
P407
P577
1997-08-29T00:00:00Z