Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae.
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Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signalingSirtuins: Sir2-related NAD-dependent protein deacetylasesSIRT1 negatively regulates the mammalian target of rapamycinRecent developments in yeast agingNicotinamide riboside kinase structures reveal new pathways to NAD+Sir2-independent life span extension by calorie restriction in yeastEpigenetic regulation of caloric restriction in agingLife span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9Increased life span due to calorie restriction in respiratory-deficient yeastCharacterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesisReversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gammaHuman SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.Phosphorylation of HuR by Chk2 regulates SIRT1 expressionSilent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activityInteractions between E2F1 and SirT1 regulate apoptotic response to DNA damageRole for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycleA role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagySubcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoformsExtension of chronological life span in yeast by decreased TOR pathway signalingThe mammalian SIR2alpha protein has a role in embryogenesis and gametogenesisSir2 mediates longevity in the fly through a pathway related to calorie restrictionStructural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylasesExtending healthy life span--from yeast to humansLessons on longevity from budding yeastResveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterasesAMP-activated protein kinase, stress responses and cardiovascular diseasesNutrient-sensitive mitochondrial NAD+ levels dictate cell survivalGenome-environment interactions that modulate aging: powerful targets for drug discoverySingle-gene mutations and healthy ageing in mammalsSIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus.Replicative and chronological aging in Saccharomyces cerevisiae.Chromatin regulation and genome maintenance by mammalian SIRT6Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetesThe neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodiesResveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life spanSHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegansThe human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylaseHormonal control of androgen receptor function through SIRT1Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
P2860
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P2860
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae.
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@ast
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@en
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@nl
type
label
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@ast
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@en
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@nl
prefLabel
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@ast
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@en
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@nl
P2093
P3181
P1433
P1476
Requirement of NAD and SIR2 fo ...... n in Saccharomyces cerevisiae.
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.289.5487.2126
P407
P577
2000-09-22T00:00:00Z