Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding.
about
A membrane protein required for dislocation of misfolded proteins from the ERCharacterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ.Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulumGetting in and out from calnexin/calreticulin cyclesInhibition of p97-dependent protein degradation by Eeyarestatin IMisfolded proteins are sorted by a sequential checkpoint mechanism of ER quality controlEDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sitesFree-oligosaccharide control in the yeast Saccharomyces cerevisiae: roles for peptide:N-glycanase (Png1p) and vacuolar mannosidase (Ams1p).Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway.ADD66, a gene involved in the endoplasmic reticulum-associated degradation of alpha-1-antitrypsin-Z in yeast, facilitates proteasome activity and assembly.Quality control of inner nuclear membrane proteins by the Asi complex.Defining the glycan destruction signal for endoplasmic reticulum-associated degradationAn HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transportTraffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulatorSubstrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase familyAutoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p.Sel1p/Ubx2p participates in a distinct Cdc48p-dependent endoplasmic reticulum-associated degradation pathway.Identification of yeast proteins necessary for cell-surface function of a potassium channel.Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.Genomewide analysis reveals novel pathways affecting endoplasmic reticulum homeostasis, protein modification and quality control.Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation.Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiaeRoles of molecular chaperones in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD)AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradationEeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathwaysEDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimmingFree oligosaccharides to monitor glycoprotein endoplasmic reticulum-associated degradation in Saccharomyces cerevisiaeEvasion of endoplasmic reticulum surveillance makes Wsc1p an obligate substrate of Golgi quality controlInterplay of substrate retention and export signals in endoplasmic reticulum quality control.ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.Probing for membrane domains in the endoplasmic reticulum: retention and degradation of unassembled MHC class I molecules.A nucleus-based quality control mechanism for cytosolic proteinsEndoplasmic reticulum localized PerA is required for cell wall integrity, azole drug resistance, and virulence in Aspergillus fumigatus.Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling.A role for N-glycanase in the cytosolic turnover of glycoproteins.Two distinctly localized p-type ATPases collaborate to maintain organelle homeostasis required for glycoprotein processing and quality controlInositol deacylation by Bst1p is required for the quality control of glycosylphosphatidylinositol-anchored proteins.Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic mice.
P2860
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P2860
Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Distinct retrieval and retenti ...... mic reticulum protein folding.
@ast
Distinct retrieval and retenti ...... mic reticulum protein folding.
@en
Distinct retrieval and retenti ...... mic reticulum protein folding.
@nl
type
label
Distinct retrieval and retenti ...... mic reticulum protein folding.
@ast
Distinct retrieval and retenti ...... mic reticulum protein folding.
@en
Distinct retrieval and retenti ...... mic reticulum protein folding.
@nl
prefLabel
Distinct retrieval and retenti ...... mic reticulum protein folding.
@ast
Distinct retrieval and retenti ...... mic reticulum protein folding.
@en
Distinct retrieval and retenti ...... mic reticulum protein folding.
@nl
P2093
P2860
P921
P356
P1476
Distinct retrieval and retenti ...... mic reticulum protein folding.
@en
P2093
P2860
P304
P356
10.1083/JCB.200106123
P407
P577
2001-10-29T00:00:00Z