Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease
about
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathwayDeconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purposeMolecular pathways for intracellular cholesterol accumulation: common pathogenic mechanisms in Niemann-Pick disease Type C and cystic fibrosisTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsProtein degradation pathways in Parkinson's disease: curse or blessingDysregulation of autophagy and mitochondrial function in Parkinson's diseaseHow Parkinsonian toxins dysregulate the autophagy machineryCdk5 phosphorylates dopamine D2 receptor and attenuates downstream signalingAnti-diabetes drug pioglitazone ameliorates synaptic defects in AD transgenic mice by inhibiting cyclin-dependent kinase5 activityBax interacting factor-1 promotes survival and mitochondrial elongation in neuronsAssociation of Endophilin B1 with Cytoplasmic Vesicles.Single point mutation in Bin/Amphiphysin/Rvs (BAR) sequence of endophilin impairs dimerization, membrane shaping, and Src homology 3 domain-mediated partnership.Cdk5 activity in the brain - multiple paths of regulation.Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human diseaseAt the Fulcrum in Health and Disease: Cdk5 and the Balancing Acts of Neuronal Structure and Physiology.Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation(4-[6-(4-isopropoxyphenyl)pyrazolo [1,5-a]pyrimidin-3-yl] quinoline) is a novel inhibitor of autophagyPhosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function.Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy.Trehalose, an mTOR independent autophagy inducer, alleviates human podocyte injury after puromycin aminonucleoside treatment.Absence of the Cdk5 activator p35 causes adult-onset neurodegeneration in the central brain of DrosophilaTruncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancersScreening for a single-chain variable-fragment antibody that can effectively neutralize the cytotoxicity of the Vibrio parahaemolyticus thermolabile hemolysin.Phosphorylation of CHIP at Ser20 by Cdk5 promotes tAIF-mediated neuronal death.Bif-1 haploinsufficiency promotes chromosomal instability and accelerates Myc-driven lymphomagenesis via suppression of mitophagyMelatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation.Loss of endophilin-B1 exacerbates Alzheimer's disease pathologyMethylene blue induces macroautophagy through 5' adenosine monophosphate-activated protein kinase pathway to protect neurons from serum deprivationTFP5 prevents 1-methyl-4-phenyl pyridine ion-induced neurotoxicity in mouse cortical neurons.PSEA: Kinase-specific prediction and analysis of human phosphorylation substrates.Axonal degeneration as a therapeutic target in the CNS.Autophagy and Its Comprehensive Impact on ALS.Defective autophagy in Parkinson's disease: role of oxidative stress.Programmed cell death in Parkinson's diseaseThe cyclin-dependent kinase family in the social amoebozoan Dictyostelium discoideum.Mechanism and Regulation of Autophagy and Its Role in Neuronal Diseases.The Role of Cdk5 in Alzheimer's Disease.Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses.Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection.
P2860
Q22676705-76BF09A4-EAC8-4BD6-AD98-C9B9280BC987Q24306217-795D509C-A5D5-4C8A-AD6A-E89E06A21734Q26785491-933F9402-A24E-44C9-B81D-B6261D91EB01Q26826845-A85E96B1-4043-4DB5-BB7A-698A8950992DQ26827580-F898FBC6-ABB0-4915-822A-A3D60F720D13Q27026029-0094158B-6DB0-4806-BB76-22574F449823Q28071890-B690EDB7-326F-4DE1-A411-75A1416D4175Q28392567-72725614-E645-4838-885B-00968F027256Q28393537-E76508F2-2C2A-4E18-91C3-6A99D50DDC40Q28546302-F9EB696C-B8F9-4341-9736-A8A3C1775DA0Q28588501-008624C9-C7BA-416C-91CD-F0FECD866A6FQ30008877-6E03F427-1786-4C9B-9A8C-E8E0BAE9FDB1Q30010188-B00ECD95-BCAB-4024-86BB-A3AB32829A62Q33687591-F2072D4F-3107-4690-B226-F478B242BBEBQ34306431-C0DAAB4A-19F9-49B1-92C2-EE0B79371028Q34418930-B994D76A-A1BD-40CD-A8F7-8C9100C48656Q34516761-CFD6A440-3871-4B1A-8D75-B802670301A8Q34954139-4DB95B2C-3C74-4DA9-959C-7B5E40A2D90FQ35315489-51AF81A3-41FB-4E01-8C25-1CEC5D50484FQ35423634-CFBF9363-04C7-4687-9E64-E8282739474CQ35439721-3A831777-7CA3-4197-9DA6-8F798C222390Q35794568-25F94B10-07BF-4D80-A9B5-56A4AE052358Q35919944-677A9709-E3DE-4A97-B01C-5B781C360957Q36155674-E34D9215-07A0-4FAB-8FB1-DAD79BD4A6BFQ36472440-148B90A7-F064-45B6-9346-4B4F691D1551Q36654134-A18AEA75-87F0-4326-B6E8-07CD18A946B8Q36777303-21E85570-DF95-4F0C-91B7-1F6300775E42Q36812205-2C921187-4EBB-4AF8-BDCE-951934C6725DQ36812658-706A34AE-0E38-4B84-A7F3-366E74C96CF9Q37288349-6342FCC0-DA70-4B67-828E-4F331EB52025Q37673104-9004F55E-0FA7-4DB9-95A6-9B6CCDDB02FBQ37990880-C3D83B29-0DDF-4FE6-84D7-78F0968BFF1FQ38029001-48121006-E54F-42AD-982E-48B4E821FE83Q38035191-840E0654-242C-4F91-A931-F7291E4A67C5Q38036233-F6D680FB-15B2-4329-8B82-BF886A6AD628Q38131284-9387B2A7-AADF-46F8-BCF3-23CFEDD1EE30Q38260329-E51DA80E-85E1-44D9-B2AC-8C893B7C3D72Q38557958-8B978FFC-0D7F-4A67-8C7E-B5B2D82F4A17Q38587949-2FE58178-6106-49C5-8321-C7174CA3EB9CQ38705560-E58D9FB5-35CF-4E08-9DE9-789B1BD27E53
P2860
Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease
description
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Mai 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/05/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/05/01)
@nl
наукова стаття, опублікована в травні 2011
@uk
مقالة علمية (نشرت في مايو 2011)
@ar
name
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@ast
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@en
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@nl
type
label
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@ast
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@en
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@nl
prefLabel
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@ast
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@en
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Cdk5-mediated phosphorylation ...... models of Parkinson's disease
@en
P2093
Anthony Y Cheung
Nancy Y Ip
Patrick K Yeung
Rebecca H K Lee
Sookja K Chung
Zelda H Cheung
P2860
P2888
P304
P3181
P356
10.1038/NCB2217
P577
2011-04-17T00:00:00Z
P6179
1013902810