Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
about
J protein mutations and resulting proteostasis collapseMutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophyRBR E3 ubiquitin ligases: new structures, new insights, new questionsStructural Basis of Defects in the Sacsin HEPN Domain Responsible for Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS)Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ.Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function.HSPA1A-independent suppression of PARK2 C289G protein aggregation by human small heat shock proteinsTranslational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.Diversity in the regulation of autophagy and mitophagy: lessons from Parkinson's disease.Molecular chaperones in Parkinson's disease--present and futureMitochondrial dynamics and Parkinson's disease: focus on parkin.Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy.HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle.Forms, crosstalks, and the role of phospholipid biosynthesis in autophagy.Opportunities and challenges for molecular chaperone modulation to treat protein-conformational brain diseasesMolecular chaperones and neuronal proteostasis.Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues.Protein kinase CK2 modulates HSJ1 function through phosphorylation of the UIM2 domain.Emerging roles and underlying molecular mechanisms of DNAJB6 in cancerA rare recessive distal hereditary motor neuropathy with HSJ1 chaperone mutation.Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G.Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies.The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosisReply: The role of DNAJB2 in amyotrophic lateral sclerosis.Identification of a Large DNAJB2 Deletion in a Family with Spinal Muscular Atrophy and Parkinsonism.Phenotype and natural history of inherited neuropathies caused by HSJ1 c.352+1G>A mutation.DNAJ Proteins in neurodegeneration: essential and protective factors.Structural modelling of the DNAJB6 oligomeric chaperone shows a peptide-binding cleft lined with conserved S/T-residues at the dimer interface.
P2860
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P2860
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
description
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Januar 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/01/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/01/01)
@nl
наукова стаття, опублікована в січні 2011
@uk
مقالة علمية (نشرت عام 2011)
@ar
name
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@ast
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@en
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@nl
type
label
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@ast
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@en
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@nl
prefLabel
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@ast
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@en
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@nl
P2093
P2860
P921
P3181
P356
P1476
Molecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutant
@en
P2093
Johanna M. Rose
Michael E. Cheetham
Philip A. Robinson
Sergey S. Novoselov
P2860
P3181
P356
10.1093/HMG/DDQ428
P577
2011-01-01T00:00:00Z