A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis
about
Fibroblast Growth Factor Signaling in Metabolic RegulationProinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1.Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial CellsAn integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1.Fibroblast growth factor-mediated crosstalk in cancer etiology and treatment.The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis.Fibroblast Growth Factor 1-Transfected Adipose-Derived Mesenchymal Stem Cells Promote Angiogenic Proliferation.Integrative Bioinformatic Analysis of Transcriptomic Data Identifies Conserved Molecular Pathways Underlying Ionizing Radiation-Induced Bystander Effects (RIBE).Secreted Phospholipase A2 Type IIA (sPLA2-IIA) Activates Integrins in an Allosteric Manner.
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A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis
description
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artículu científicu espublizáu en 2013
@ast
im Januar 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/01/01)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/01/01)
@nl
наукова стаття, опублікована в січні 2013
@uk
name
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@ast
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@en
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@nl
type
label
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@ast
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@en
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@nl
prefLabel
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@ast
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@en
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@nl
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P921
P1433
P1476
A dominant-negative FGF1 mutan ...... tumorigenesis and angiogenesis
@en
P2093
Jun Saegusa
Kyoko Nishikawa
Masaaki Fujita
Naomasa Kawaguchi
Nariaki Matsuura
Seiji Mori
Teruya Kaneda
Yoko K. Takada
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P304
P356
10.1371/JOURNAL.PONE.0057927
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P577
2013-01-01T00:00:00Z