The immunological synapse: a molecular machine controlling T cell activation
about
The instructive role of dendritic cells on T-cell responsesCentriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systemsMechanisms behind functional avidity maturation in T cellsHLA-DR alpha 2 mediates negative signalling via binding to Tirc7 leading to anti-inflammatory and apoptotic effects in lymphocytes in vitro and in vivoGAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytesSleep and immune functionMechanism for down-regulation of CD28 by Nef.Dynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transductionWiskott-Aldrich syndrome protein controls antigen-presenting cell-driven CD4+ T-cell motility by regulating adhesion to intercellular adhesion molecule-1Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASPGalectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapseCalcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteinsA single class II myosin modulates T cell motility and stopping, but not synapse formationβ-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanismDynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector moleculesMedical immunology: a new journal for a new subspecialty.Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug actionKv1.3 potassium channels are localized in the immunological synapse formed between cytotoxic and target cellsBasophils function as antigen-presenting cells for an allergen-induced T helper type 2 responseThe extracellular architecture of adherens junctions revealed by crystal structures of type I cadherinsPerforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells.Follicular helper T cells: lineage and locationRegulation of T-cell activation by phosphodiesterase 4B2 requires its dynamic redistribution during immunological synapse formationThe human natural killer cell immune synapseT cell activationTopological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonistsRegulation of lymphocyte apoptosis by interferon regulatory factor 4 (IRF-4)Role of diacylglycerol kinase alpha in the attenuation of receptor signalingQuantitative challenges in understanding ligand discrimination by alphabeta T cellsThe quantal theory of how the immune system discriminates between "self and non-self"In vivo imaging approaches in animal models of rheumatoid arthritisControl of T lymphocyte morphology by the GTPase Rho.Cell membrane array fabrication and assay technology.Modeling T cell antigen discrimination based on feedback control of digital ERK responsesActin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.New Insights into How Trafficking Regulates T Cell Receptor SignalingDynamic Regulation of TCR-Microclusters and the Microsynapse for T Cell ActivationThe Role of Lymphatic Niches in T Cell DifferentiationDevelopment of lifitegrast: a novel T-cell inhibitor for the treatment of dry eye diseaseThe Molecular Architecture of Cell Adhesion: Dynamic Remodeling Revealed by Videonanoscopy
P2860
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P2860
The immunological synapse: a molecular machine controlling T cell activation
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The immunological synapse: a molecular machine controlling T cell activation
@ast
The immunological synapse: a molecular machine controlling T cell activation
@en
The immunological synapse: a molecular machine controlling T cell activation
@nl
type
label
The immunological synapse: a molecular machine controlling T cell activation
@ast
The immunological synapse: a molecular machine controlling T cell activation
@en
The immunological synapse: a molecular machine controlling T cell activation
@nl
prefLabel
The immunological synapse: a molecular machine controlling T cell activation
@ast
The immunological synapse: a molecular machine controlling T cell activation
@en
The immunological synapse: a molecular machine controlling T cell activation
@nl
P2093
P3181
P1433
P1476
The immunological synapse: a molecular machine controlling T cell activation
@en
P2093
M L Dustin
S K Bromley
P3181
P356
10.1126/SCIENCE.285.5425.221
P407
P577
1999-07-09T00:00:00Z