Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins
about
Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3PTEN as an effector in the signaling of antimigratory G protein-coupled receptorEdg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturationG-protein Coupled Receptor Signaling in Pluripotent Stem Cell-derived Cardiovascular Cells: Implications for Disease ModelingSphingosine kinase 1/sphingosine 1-phosphate signalling pathway as a potential therapeutic target of pulmonary hypertensionSphingosine 1-phosphate signallingThe role of sphingosine-1-phosphate in endothelial barrier functionSphingolipid signaling in metabolic disordersLipid phosphate phosphatase (LPP3) and vascular developmentNrg-1 belongs to the endothelial differentiation gene family of G protein-coupled sphingosine-1-phosphate receptorsB plexins activate Rho through PDZ-RhoGEFSphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptaseInhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.S1pr2/Gα13 signaling controls myocardial migration by regulating endoderm convergence.G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.Novel GPCR screening approach: indirect identification of S1P receptor agonists in antagonist screening using a calcium assay.CCL3, acting via the chemokine receptor CCR5, leads to independent activation of Janus kinase 2 (JAK2) and Gi proteins.Sphingosine-1-phosphate elicits receptor-dependent calcium signaling in retinal amacrine cellsThe impact of sphingosine kinase-1 in head and neck cancer.Sphingolipids affect fibrinogen-induced caveolar transcytosis and cerebrovascular permeability.Sphingosine 1-phosphate signalling in mammalian cells.HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate.Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection.Systemic distribution, subcellular localization and differential expression of sphingosine-1-phosphate receptors in benign and malignant human tissues.Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules.Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactionsInhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation.Regulation of cancer cell migration and invasion by sphingosine-1-phosphateActivation of heterotrimeric G proteins by Smoothened.Endothelial differentiation gene-1, a new downstream gene is involved in RTEF-1 induced angiogenesis in endothelial cells.Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells.The alpha subunit of the G protein G13 regulates activity of one or more Gli transcription factors independently of smoothened.Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1 - Jekyll Hidden behind HydeTotal proteome analysis identifies migration defects as a major pathogenetic factor in immunoglobulin heavy chain variable region (IGHV)-unmutated chronic lymphocytic leukemia.Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina.FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia.The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH
P2860
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P2860
Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Differential coupling of the s ...... s of heterotrimeric G proteins
@ast
Differential coupling of the s ...... s of heterotrimeric G proteins
@en
Differential coupling of the s ...... s of heterotrimeric G proteins
@nl
type
label
Differential coupling of the s ...... s of heterotrimeric G proteins
@ast
Differential coupling of the s ...... s of heterotrimeric G proteins
@en
Differential coupling of the s ...... s of heterotrimeric G proteins
@nl
prefLabel
Differential coupling of the s ...... s of heterotrimeric G proteins
@ast
Differential coupling of the s ...... s of heterotrimeric G proteins
@en
Differential coupling of the s ...... s of heterotrimeric G proteins
@nl
P2093
P3181
P356
P1476
Differential coupling of the s ...... s of heterotrimeric G proteins
@en
P2093
P304
P3181
P356
10.1074/JBC.274.39.27351
P407
P577
1999-09-24T00:00:00Z