The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
about
CD164 regulates the tumorigenesis of ovarian surface epithelial cells through the SDF-1α/CXCR4 axisStructures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonistsThe GABAB receptor interacts directly with the related transcription factors CREB2 and ATFxCXCR4 in breast cancer: oncogenic role and therapeutic targetingDiversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesCXCL12 chemokine and GABA neurotransmitter systems crosstalk and their putative rolesTargeting the molecular and cellular interactions of the bone marrow niche in immunologic diseaseCXCL12 chemokine and its receptors as major players in the interactions between immune and nervous systemsImmature B Cell Egress from Bone Marrow Is SOCS3 IndependentStructure of mouse IP-10, a chemokineHeterologous quaternary structure of CXCL12 and its relationship to the CC chemokine familyOligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors.Dynamic filopodia are required for chemokine-dependent intracellular polarization during guided cell migration in vivoHuman β-defensin 3 induces STAT1 phosphorylation, tyrosine phosphatase activity, and cytokine synthesis in T cells.JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activationJak3 is involved in dendritic cell maturation and CCR7-dependent migration.Anti-HIV small-molecule binding in the peptide subpocket of the CXCR4:CVX15 crystal structure.CXC chemokine receptor 4 expression, CXC chemokine receptor 4 activation, and wild-type nucleophosmin are independently associated with unfavorable prognosis in patients with acute myeloid leukemiaChemokine coreceptor signaling in HIV-1 infection and pathogenesis.T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromesEmerging concepts and approaches for chemokine-receptor drug discovery.Chemokine receptor oligomerization and allostery.Vav1 and Rac control chemokine-promoted T lymphocyte adhesion mediated by the integrin alpha4beta1VEGFR-3 and CXCR4 as predictive markers for treatment with fluorouracil, leucovorin plus either oxaliplatin or cisplatin in patients with advanced esophagogastric cancer: a comparative study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).Chemokine signaling in cancer: Implications on the tumor microenvironment and therapeutic targetingLigand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells.Involvement of mTOR in CXCL12 mediated T cell signaling and migration.Heterotrimeric G protein signaling outside the realm of seven transmembrane domain receptorsChemokine receptor homo- or heterodimerization activates distinct signaling pathways.Chemokines and their receptors in infectious disease.A PKA-Csk-pp60Src signaling pathway regulates the switch between endothelial cell invasion and cell-cell adhesion during vascular sprouting.Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.Consequences of ChemR23 heteromerization with the chemokine receptors CXCR4 and CCR7.Upregulation of stromal cell-derived factor 1 (SDF-1) is associated with macrophage infiltration in renal ischemia-reperfusion injury.Novel role for NFAT3 in ERK-mediated regulation of CXCR4Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: molecular modeling and experimental validation.Human neonatal cardiovascular progenitors: unlocking the secret to regenerative ability.Chemokine receptors: emerging opportunities for new anti-HIV therapies.
P2860
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P2860
The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@ast
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@en
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@nl
type
label
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@ast
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@en
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@nl
prefLabel
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@ast
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@en
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@nl
P2093
P3181
P356
P1433
P1476
The chemokine SDF-1alpha trigg ...... activates the JAK/STAT pathway
@en
P2093
A J Vila-Coro
A Martín De Ana
C Martínez-A
J M Rodríguez-Frade
M C Moreno-Ortíz
P2860
P2888
P304
P3181
P356
10.1038/23382
P407
P577
1999-10-01T00:00:00Z
P6179
1048075487