Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation - sprookjes - yvandenbroek - TriplyDB

Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation

Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation

http://www.wikidata.org/entity/Q28177120

about

CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?Medicine. Activating a repressor Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes DLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiency Structure-specific binding of MeCP2 to four-way junction DNA through its methyl CpG-binding domain Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease MeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addiction Rett Syndrome: Crossing the Threshold to Clinical Translation MECP2 disorders: from the clinic to mice and back MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?Role of mecp2 in experience-dependent epigenetic programming Genetic modifiers of MeCP2 function in Drosophila.Structure and organization of chromatin fiber in the nucleus Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins MeCP2: the chromatin connection and beyond Components of the DNA methylation system of chromatin control are RNA-binding proteins Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo Methyl-CpG binding protein 2 (MeCP2) localizes at the centrosome and is required for proper mitotic spindle organization MicroRNAs in addiction: adaptation's middlemen?Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.Biophysical analysis and small-angle X-ray scattering-derived structures of MeCP2-nucleosome complexes.Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization.Cohesin interaction with centromeric minichromosomes shows a multi-complex rod-shaped structure.Merging data from genetic and epigenetic approaches to better understand autistic spectrum disorder.A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets.High levels of MeCP2 depress MHC class I expression in neuronal cells.Interchromatidal central ridge and transversal symmetry in early metaphasic human chromosome one.The Crucial Role of DNA Methylation and MeCP2 in Neuronal Function MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5.Unique physical properties and interactions of the domains of methylated DNA binding protein 2.Methyl-CpG binding proteins: specialized transcriptional repressors or structural components of chromatin?Recent advances in MeCP2 structure and function.Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics Effect of DNA groove binder distamycin A upon chromatin structure.High novelty-seeking rats are resilient to negative physiological effects of the early life stress.Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies Brd2/RING3 interacts with a chromatin-binding domain in the Kaposi's Sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1.

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Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation

http://www.wikidata.org/entity/Q28177120

description

2003 nî lūn-bûn

@nan

2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի օգոստոսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Chromatin compaction by human ...... the absence of DNA methylation

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Chromatin compaction by human ...... the absence of DNA methylation

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Chromatin compaction by human ...... the absence of DNA methylation

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type

label

Chromatin compaction by human ...... the absence of DNA methylation

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Chromatin compaction by human ...... the absence of DNA methylation

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Chromatin compaction by human ...... the absence of DNA methylation

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prefLabel

Chromatin compaction by human ...... the absence of DNA methylation

@ast

Chromatin compaction by human ...... the absence of DNA methylation

@en

Chromatin compaction by human ...... the absence of DNA methylation

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P1433

Journal of Biological Chemistry

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Chromatin compaction by human ...... the absence of DNA methylation

@en

P2093

Christopher L Woodcock

http://www.w3.org/2001/XMLSchema#string

Jeffrey C Hansen

http://www.w3.org/2001/XMLSchema#string

Nick Adkins

http://www.w3.org/2001/XMLSchema#string

Paul A Wade

http://www.w3.org/2001/XMLSchema#string

Philippe T Georgel

http://www.w3.org/2001/XMLSchema#string

Rachel A Horowitz-Scherer

http://www.w3.org/2001/XMLSchema#string

P2860

Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA

Nucleosomes, linker DNA, and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin

The solution structure of the domain from MeCP2 that binds to methylated DNA

Mutations in the gene encoding methyl-CpG-binding protein 2 cause Rett syndrome

Corepressor-dependent silencing of chromosomal regions encoding neuronal genes

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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scholarly article

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644641

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10.1074/JBC.M305308200

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34

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278

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2003-08-22T00:00:00Z

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12788925

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P921

DNA methylation