Peptide and nonpeptide ligands for the nociceptin/orphanin FQ receptor ORL1: research tools and potential therapeutic agents
about
Small-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): ligand-based analysis of structural factors influencing intrinsic activity at NOPDiscovery of the first small-molecule opioid pan antagonist with nanomolar affinity at mu, delta, kappa, and nociceptin opioid receptorsThe nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medicationsStructure-based virtual screening of the nociceptin receptor: hybrid docking and shape-based approaches for improved hit identification.The Nociceptin Receptor as an Emerging Molecular Target for Cocaine AddictionIn vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptorEmerging analgesics in cancer pain management.Activities of mixed NOP and mu-opioid receptor ligands.Neuropeptides as possible targets in sleep disorders.The hypocretin/orexin receptor: therapeutic prospective in sleep disorders.Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility.A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor.Development of nociceptin receptor (NOP) agonists and antagonists.Emerging treatments for narcolepsy and its related disorders.Recently patented and promising ORL-1 ligands: where have we been and where are we going?Expert opinion on pharmacotherapy of narcolepsy.The design and synthesis of a novel quinolizidine template for potent opioid and opioid receptor-like (ORL1, NOP) receptor ligands.Exogenous, but not endogenous nociceptin modulates mesolimbic dopamine release in mice.Recent advances in the treatment of narcolepsy.In silico study of the structurally similar ORL1 receptor agonist and antagonist pairs reveal possible mechanism of receptor activation.Neuropeptide orphanin FQ inhibits dendritic morphogenesis through activation of RhoA.Synthesis and analgesic effects of novel β2-tryptophan hexapeptide analogsElevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease
P2860
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P2860
Peptide and nonpeptide ligands for the nociceptin/orphanin FQ receptor ORL1: research tools and potential therapeutic agents
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@ast
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@en
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@nl
type
label
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@ast
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@en
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@nl
prefLabel
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@ast
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@en
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@nl
P2860
P1433
P1476
Peptide and nonpeptide ligands ...... d potential therapeutic agents
@en
P2093
Nurulain Zaveri
P2860
P304
P356
10.1016/S0024-3205(03)00387-4
P407
P577
2003-06-27T00:00:00Z