Pyogenic bacterial infections in humans with IRAK-4 deficiency
about
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiencyIRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humansA TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signalingLys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activationPathogen recognition and inflammatory signaling in innate immune defensesPyogenic bacterial infections in humans with MyD88 deficiencyRecombinant bactericidal/permeability-increasing protein rBPI21 protects against pneumococcal diseaseBench-to-bedside review: understanding genetic predisposition to sepsisTLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxinsN. meningitidis and TLR Polymorphisms: A Fascinating Immunomodulatory NetworkThe Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine AntigensImpact of Bacterial and Human Genetic Variation on Staphylococcus aureus InfectionsSevere infectious diseases of childhood as monogenic inborn errors of immunityInflammasome/IL-1β Responses to Streptococcal PathogensPrimary immunodeficiencies of pattern recognition receptorsIL-1 Receptor-Associated Kinase Signaling and Its Role in Inflammation, Cancer Progression, and Therapy ResistancePopulation genetic tools for dissecting innate immunity in humansHelical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signallingEducational paper: Primary immunodeficiencies in children: a diagnostic challengeHost-pathogen interactions between the skin and Staphylococcus aureus.Recent Progress in the Molecular Recognition and Therapeutic Importance of Interleukin-1 Receptor-Associated Kinase 4Neutrophils: Between host defence, immune modulation, and tissue injuryHuman IFNAR2 deficiency: Lessons for antiviral immunityIRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assemblySelective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunityEvolutionary dynamics of human Toll-like receptors and their different contributions to host defenseIRAK-4 inhibitors for inflammationNF-kappaB-related genetic diseasesTLR signalingDual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear CellsThe role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signalingA Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosisIgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patientsSystems biology of innate immunityRole of TLR signaling in Francisella tularensis-LPS-induced, antibody-mediated protection against Francisella tularensis challenge.Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ribavirin therapy in chronic hepatitis C patients.A naturally occurring variant in human TLR9, P99L, is associated with loss of CpG oligonucleotide responsiveness.Structural dynamic analysis of apo and ATP-bound IRAK4 kinaseFull-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease.
P2860
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P2860
Pyogenic bacterial infections in humans with IRAK-4 deficiency
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@ast
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@en
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@nl
type
label
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@ast
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@en
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@nl
prefLabel
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@ast
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@en
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@nl
P2093
P50
P3181
P356
P1433
P1476
Pyogenic bacterial infections in humans with IRAK-4 deficiency
@en
P2093
Abdulaziz Al-Ghonaium
Adrian Ozinsky
Alan Aderem
Carole Elbim
Claire Fieschi
David Lammas
Graham Davies
Hassan Al-Rayes
Haysam Tufenkeji
Husn H Frayha
P304
P3181
P356
10.1126/SCIENCE.1081902
P407
P50
P577
2003-03-13T00:00:00Z