RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity
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Activation state-dependent interaction between Galphai and p67phoxSelective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiationRGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory.Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1AGalphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domainExpansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimersThe GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunitsActivators of G protein signaling in the kidneyRGS14 at the interface of hippocampal signaling and synaptic plasticityMolecular architecture of G o and the structural basis for RGS16-mediated deactivationStructural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein Subunit MutantsRegulators of G-protein signaling in the heart and their potential as therapeutic targets.The RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast.Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from GαiAutoprocessing of the Vibrio cholerae RTX toxin by the cysteine protease domainRGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shockRGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathwaysActivation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8ARegulator of G-protein signaling 14 (RGS14) is a selective H-Ras effectorRegulation of longevity by regulator of G-protein signaling protein, LocoRole of layer 6 of V2 visual cortex in object-recognition memoryThe RGS14 GoLoco domain discriminates among Galphai isoformsRetinal ON bipolar cells express a new PCP2 splice variant that accelerates the light responseRegulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.The evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamicsStructural determinants underlying the temperature-sensitive nature of a Galpha mutant in asymmetric cell division of Caenorhabditis elegans.Sensorimotor enhancement in mouse mutants lacking the Purkinje cell-specific Gi/o modulator, Pcp2(L7).Real-time detection of basal and stimulated G protein GTPase activity using fluorescent GTP analogues.A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction.Inhibition of Gαi activity by Gβγ is mediated by PI 3-kinase-γ- and cSrc-dependent tyrosine phosphorylation of Gαi and recruitment of RGS12.Light-dependent phosphorylation of the carboxy tail of mouse melanopsin.Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions.Amphetamine up-regulates activator of G-protein signaling 1 mRNA and protein levels in rat frontal cortex: the role of dopamine and glucocorticoid receptors.Regulators of G-protein signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity.Development of inhibitors of heterotrimeric Gαi subunitsRGS14 is a bifunctional regulator of Galphai/o activity that exists in multiple populations in brain.Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis.Nucleobindin 1 is a calcium-regulated guanine nucleotide dissociation inhibitor of G{alpha}i1.The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells.
P2860
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P248
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P2860
RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@ast
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@en
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@nl
type
label
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@ast
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@en
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@nl
prefLabel
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@ast
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@en
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@nl
P2093
P2860
P3181
P356
P1476
RGS12 and RGS14 GoLoco motifs ...... issociation inhibitor Activity
@en
P2093
D P Siderovski
H Tronchère
L De Vries
M Gist Farquhar
R A Morris
R J Kimple
P2860
P304
P3181
P356
10.1074/JBC.M103208200
P407
P577
2001-08-03T00:00:00Z