Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
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Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timerTumor necrosis factor receptor 1 is an ATPase regulated by silencer of death domainRegulation of the intrinsic apoptosis pathway by reactive oxygen speciesAtomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosisNegative regulation of the Apaf-1 apoptosome by Hsp70HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentationStructure of the apoptotic protease-activating factor 1 bound to ADPInduced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting proteinRole of Apaf-1, a key regulator of apoptosis, in melanoma progression and chemoresistanceAntineoplastic effect of beta-elemene on prostate cancer cells and other types of solid tumour cellsRecruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexesElevated extracellular [K+] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c releaseThe PYRIN domain in signal transductionHis26 protonation in cytochrome c triggers microsecond β-sheet formation and heme exposure: implications for apoptosisEstrogen suppresses uterine epithelial apoptosis by inducing birc1 expressionJun kinase delays caspase-9 activation by interaction with the apoptosomeMolecular components of a cell death pathway activated by endoplasmic reticulum stressThe chaperone function of hsp70 is required for protection against stress-induced apoptosisProximal events in 7,12-dimethylbenz[a]anthracene-induced, stromal cell-dependent bone marrow B cell apoptosis: stromal cell-B cell communication and apoptosis signalingMolecular mechanisms of caspase regulation during apoptosisDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMPro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.A cytochrome c-GFP fusion is not released from mitochondria into the cytoplasm upon expression of Bax in yeast cells.Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).Type I and type II reactions in TRAIL-induced apoptosis -- results from dose-response studies.Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex.Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cellsStructure of an apoptosome-procaspase-9 CARD complex.Reactive oxygen radicals in signaling and damage in the ischemic brain.Role of JNK Activation and Mitochondrial Bax Translocation in Allicin-Induced Apoptosis in Human Ovarian Cancer SKOV3 CellsMechanism of tyrosine phosphorylation of procaspase-9 and Apaf-1 in cytosolic fractions of the cerebral cortex of newborn piglets during hypoxia.Oligomerization and activation of caspase-9, induced by Apaf-1 CARD.Arsenic trioxide - An old drug rediscovered.Caspase-3 apoptotic signaling following injury to the central nervous system.Resveratrol--from the bottle to the bedside?Activation of caspase-9, but not caspase-2 or caspase-8, is essential for heat-induced apoptosis in Jurkat cells.Stressed to death: regulation of apoptotic signaling pathways by the heat shock proteins.
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P2860
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@ast
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@en
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@nl
type
label
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@ast
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@en
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@nl
prefLabel
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@ast
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@en
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@nl
P2093
P3181
P356
P1476
Cytochrome c and dATP-mediated ...... te for procaspase-9 activation
@en
P2093
E S Alnemri
S M Srinivasula
P304
P3181
P356
10.1074/JBC.274.25.17941
P407
P577
1999-06-18T00:00:00Z