Acyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitro
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Molecular characterization of centerin, a germinal centre cell serpinImpacts of tissue-type plasminogen activator (tPA) on neuronal survivalPhysiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous systemNeuroserpin Differentiates Between Forms of Tissue Type Plasminogen Activator via pH Dependent Deacylation.Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulumLatent S49P neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodiesSerine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behaviorNeonatal Hypoxia Ischaemia: Mechanisms, Models, and Therapeutic Challenges.The tempered polymerization of human neuroserpin.Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade.AAV-mediated overexpression of neuroserpin in the hippocampus decreases PSD-95 expression but does not affect hippocampal-dependent learning and memory.Local conformational flexibility provides a basis for facile polymer formation in human neuroserpinThe complexity of tissue-type plasminogen activator: can serine protease inhibitors help in stroke management?Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicityThe intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB.Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules.Beta-amyloidolysis and glutathione in Alzheimer's disease.Structural differences between active forms of plasminogen activator inhibitor type 1 revealed by conformationally sensitive ligands.pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; implications for the control of beta-sheet A and polymerization.The low density lipoprotein receptor-related protein modulates protease activity in the brain by mediating the cellular internalization of both neuroserpin and neuroserpin-tissue-type plasminogen activator complexes.A hydrophobic patch surrounding Trp154 in human neuroserpin controls the helix F dynamics with implications in inhibition and aggregation.Two latent and two hyperstable polymeric forms of human neuroserpin.Kinetic characterization of the protein Z-dependent protease inhibitor reaction with blood coagulation factor Xa.Comparative analysis and expression of neuroserpin in Xenopus laevis.An analysis approach to identify specific functional sites in orthologous proteins using sequence and structural information: application to neuroserpin reveals regions that differentially regulate inhibitory activity.The serine protease inhibitor neuroserpin regulates the growth and maturation of hippocampal neurons through a non-inhibitory mechanism.Molecular bases of neuroserpin function and pathology.
P2860
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P2860
Acyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitro
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2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@ast
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@en
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@nl
type
label
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@ast
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@en
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@nl
prefLabel
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@ast
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@en
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@nl
P2093
P2860
P3181
P356
P1476
Acyl-enzyme complexes between ...... erpin are short-lived in vitro
@en
P2093
Bradford S Schwartz
Daniel A Lawrence
Karen Barker-Carlson
P2860
P304
P3181
P356
10.1074/JBC.M207740200
P407
P577
2002-12-06T00:00:00Z