From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
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Evidence of compromised blood-spinal cord barrier in early and late symptomatic SOD1 mice modeling ALSAtaxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALSDisulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model miceEarly presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosisEvaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosisClinical and experimental applications of sodium phenylbutyrateSperm and oocyte communication mechanisms controlling C. elegans fertilityDecreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice modelCollapse of proteostasis represents an early molecular event in Caenorhabditis elegans agingThe CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onsetGlutamate and neurotrophic factors in neuronal plasticity and diseaseProteomic profiling of cerebrospinal fluid identifies biomarkers for amyotrophic lateral sclerosisMisfolded CuZnSOD and amyotrophic lateral sclerosisALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomesRole of ROS and RNS Sources in Physiological and Pathological ConditionsPrion diseases: immunotargets and therapyQuo vadis motor neuron disease?Emerging Roles of Filopodia and Dendritic Spines in Motoneuron Plasticity during Development and DiseaseCRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseasesBlood-CNS Barrier Impairment in ALS patients versus an animal modelStem cells in the nervous systemA Drosophila model of ALS: human ALS-associated mutation in VAP33A suggests a dominant negative mechanismMicroRNA-206: a potential circulating biomarker candidate for amyotrophic lateral sclerosisThe omega-3 fatty acid eicosapentaenoic acid accelerates disease progression in a model of amyotrophic lateral sclerosisMolecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu Zn superoxide dismutaseSuperoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosisTherapeutic applications of mesenchymal stem cells for amyotrophic lateral sclerosis.Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALSInactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male miceAlsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutantsThe complex molecular biology of amyotrophic lateral sclerosis (ALS)The G336S variant in the human neurofilament-M gene does not affect its assembly or distribution: importance of the functional analysis of neurofilament variantsThe rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosisFlavin-containing monooxygenase mRNA levels are up-regulated in als brain areas in SOD1-mutant miceMechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid estersExploring new pathways of neurodegeneration in ALS: the role of mitochondria quality controlMice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome traffickingAlsin is a Rab5 and Rac1 guanine nucleotide exchange factorA neurotoxic peripherin splice variant in a mouse model of ALSLoss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress
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P2860
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
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2001 nî lūn-bûn
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2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@ast
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@en
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@nl
type
label
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@ast
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@en
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@nl
prefLabel
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@ast
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@en
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@nl
P3181
P356
P1476
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
@en
P2093
D W Cleveland
J D Rothstein
P2888
P304
P3181
P356
10.1038/35097565
P407
P577
2001-11-01T00:00:00Z
P5875
P6179
1032464423