Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
about
sameAs
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patientsThymidylate synthetase mRNA levels are increased in liver metastases of colorectal cancer patients resistant to fluoropyrimidine-based chemotherapySignal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines.Prediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast cell linesTherapeutic potential of TAS-102 in the treatment of gastrointestinal malignanciesBase excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracilRole of Akt signaling in resistance to DNA-targeted therapyThe antitumor effects of geraniol: Modulation of cancer hallmark pathways (Review)Genetic factors affecting patient responses to pancreatic cancer treatment5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signalMechanism of 5-fluorouracil required resistance in human hepatocellular carcinoma cell line Bel(7402).Identification of consensus genes and key regulatory elements in 5-fluorouracil resistance in gastric and colon cancer.Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma.Interaction between thymidylate synthase and its cognate mRNA in zebrafish embryosThe Value of Caspase-3 after the Application of Annona muricata Leaf Extract in COLO-205 Colorectal Cancer Cell Line.dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: a dual-institutional follow-up with the RTOG 9704 trial.The association between two polymorphisms in the TYMS gene and breast cancer risk: a meta-analysis.Inhibition of human gastric carcinoma cell growth by atofluding derivative N3-o-toluyl-fluorouracil.Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines.A long non-coding RNA snaR contributes to 5-fluorouracil resistance in human colon cancer cells.Association between ERCC1 and TS mRNA levels and disease free survival in colorectal cancer patients receiving oxaliplatin and fluorouracil (5-FU) adjuvant chemotherapyPharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors.5-Fluorouracil derivatives: a patent review.Amplification of thymidylate synthetase in metastatic colorectal cancer patients pretreated with 5-fluorouracil-based chemotherapy.Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies.HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy.Bosutinib plus capecitabine for selected advanced solid tumours: results of a phase 1 dose-escalation studyPemetrexed induced thymidylate synthase inhibition in non-small cell lung cancer patients: a pilot study with 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography.Vitamin D analogs enhance the anticancer activity of 5-fluorouracil in an in vivo mouse colon cancer modelEvaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil. Is it time to move forward?The role of DNA synthesis imaging in cancer in the era of targeted therapeuticsRKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients.Future potential of thymidylate synthase inhibitors in cancer therapy.Gene amplification and point mutations in pyrimidine metabolic genes in 5-fluorouracil resistant Leishmania infantum.A practical approach for assessing chemosensitivity in colorectal cancer cell lines by comparative analysis of cell viability and thymidylate synthase mRNA expression.Poly(butylcyanoacrylate) and Poly(ε-caprolactone) Nanoparticles Loaded with 5-Fluorouracil Increase the Cytotoxic Effect of the Drug in Experimental Colon CancerProspective clinical trials using a pharmacogenetic/pharmacogenomic approach.Genetic Variation of Methylenetetrahydrofolate Reductase (MTHFR) and Thymidylate Synthase (TS) Genes Is Associated with Idiopathic Recurrent Implantation FailurePredictive diagnostics in colorectal cancer: impact of genetic polymorphisms on individual outcomes and treatment with fluoropyrimidine-based chemotherapy.
P2860
Q24561669-2E7BE535-32CC-4E51-A6D8-B1707154AF97Q24795468-6D22F77A-319C-4B4B-9A20-DF3DF96FE70AQ24799458-05793796-E50E-4C89-93C7-313B7802801FQ24816504-92B9E848-A0EA-475F-B95B-7A4CCD275141Q26777679-91632EA2-106E-432F-AEC0-6230FBC6EAF6Q27863401-74B0EF4F-49AD-4BFC-A075-4D24E9F16666Q28066950-BC34172C-4587-49DF-9380-95136A784282Q28067149-80D2D9A5-536F-4B2C-B22C-99ABB5828ACDQ28075293-F3C884C3-B109-433A-9EE1-7813A825BDCAQ28384242-476B80E4-F744-4B09-A166-3BBC78C53467Q30718056-329F805F-24A1-4282-A19C-9667F9284966Q33298577-FB9DD336-652A-4C6B-BD1D-45E8470178C8Q33336057-32014EC8-F211-4A15-81BC-EE53ABAC12A2Q33582167-74775A14-3283-4D72-89AD-1825F4E44649Q33592984-F01B9C1C-489E-427D-AFFC-1B0A23D38971Q33727842-E8CA2087-84CA-4BCE-9CF1-FC6A4D7C754FQ33781340-CF05AA58-C919-400E-B853-74F141FA54F0Q33866280-DA43D42E-28F2-4443-BC41-3FD0E38E1D84Q33914993-68005F47-C8AE-41B7-808F-0CF69B17A4FCQ34043011-6385E747-E92D-4681-A848-D0D5F60F4422Q34143862-F922D11F-0F5C-4157-AFFE-102462507128Q34195899-9936B48C-0B63-480B-B22C-6D5B16215EEBQ34253978-62C53EB5-DC32-40E2-AB3A-6A5936BEBAFCQ34349053-E3190EEE-46E8-40AA-8323-0D02C001E739Q34567805-C25F526B-F84B-4E03-B3A5-45AF7109D17AQ34620205-A23DAA30-AD3C-422B-B014-3933ADF280ADQ34654819-799B7FD7-BC10-426B-B532-313144FD7A90Q34658293-CC442BCB-372A-409D-A025-E2DCF33FEE07Q34744444-96637881-808F-4D26-862D-C3ECEA96DA0FQ34777428-CB2FEDD4-BF48-4766-965D-F32F9BEF5F83Q34847802-119BD793-C111-4C1D-9AB5-93A883EF0BC6Q34907192-54BFA455-C822-4B49-A3D3-81396A15B779Q35010521-2E695AC7-59CA-4C78-AD1A-FE0B11E779F0Q35011904-6295EC7A-D525-4D6E-A48A-664C8924BE00Q35054195-BC63E8BE-FEBC-4694-A353-582C2238CEC7Q35707816-CA6AC141-9985-4E06-B94C-EBF725518F94Q35768392-8415E9A2-A6C6-4D95-9E9A-2E7BDFB1E8EDQ36028631-56AB561E-86C5-4EA7-B8F9-C5091FDDE134Q36112653-0B5071F8-2CFF-4055-AD3A-0CFE656A191DQ36117701-0A35ABA4-67CB-4B86-908D-19FDE1FC8D6F
P2860
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@ast
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@en
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@nl
type
label
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@ast
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@en
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@nl
prefLabel
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@ast
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@en
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@nl
P2093
P3181
P1476
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
@en
P2093
A H Calvert
B van Triest
C J van Groeningen
C L van der Wilt
G J Peters
H H J Backus
H L McLeod
H M Pinedo
P304
P3181
P356
10.1016/S0925-4439(02)00082-0
P407
P577
2002-07-01T00:00:00Z