SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers - sprookjes - yvandenbroek - TriplyDB

SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers

SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers

http://www.wikidata.org/entity/Q28208039

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The Slit/Robo system suppresses hepatocyte growth factor-dependent invasion and morphogenesis.SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium microRNAs exhibit high frequency genomic alterations in human cancer Guidance molecules in lung cancer Slit-Robo interactions during cortical development Inhibition of medulloblastoma cell invasion by Slit Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts.The emerging role of Slit-Robo pathway in gastric and other gastro intestinal cancers Slit/Robo pathway: a promising therapeutic target for cancer Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration.Slits affect the timely migration of neural crest cells via Robo receptor Elevated Slit2 Activity Impairs VEGF-Induced Angiogenesis and Tumor Neovascularization in EphA2-Deficient Endothelium Quantification of SLIT-ROBO transcripts in hepatocellular carcinoma reveals two groups of genes with coordinate expression Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity.Variability in the incidence of miRNAs and genes in fragile sites and the role of repeats and CpG islands in the distribution of genetic material.Molecular pathways and therapeutic targets in lung cancer MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma.Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes.Glucocorticoid regulation of SLIT/ROBO tumour suppressor genes in the ovarian surface epithelium and ovarian cancer cells.USP33, a new player in lung cancer, mediates Slit-Robo signaling.A systematic analysis on DNA methylation and the expression of both mRNA and microRNA in bladder cancer Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer.Involvement of the SLIT/ROBO pathway in follicle development in the fetal ovary.Inactivation of SLIT2-ROBO1/2 pathway in premalignant lesions of uterine cervix: clinical and prognostic significances Slit2 inactivates GSK3β to signal neurite outgrowth inhibition.Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation.USP33 mediates Slit-Robo signaling in inhibiting colorectal cancer cell migration.ADAM9 up-regulates N-cadherin via miR-218 suppression in lung adenocarcinoma cells Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway.Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis.The role of estrogen in the initiation of breast cancer Expression and roles of Slit/Robo in human ovarian cancer.Tumor tissue microRNA expression in association with triple-negative breast cancer outcomes Promoter hypermethylation of HS3ST2, SEPTIN9 and SLIT2 combined with FGFR3 mutations as a sensitive/specific urinary assay for diagnosis and surveillance in patients with low or high-risk non-muscle-invasive bladder cancer.Epigenetic Repression of miR-218 Promotes Esophageal Carcinogenesis by Targeting ROBO1 SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinoma

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SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers

http://www.wikidata.org/entity/Q28208039

description

2002 nî lūn-bûn

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2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

SLIT2, a human homologue of th ...... ted in lung and breast cancers

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SLIT2, a human homologue of th ...... ted in lung and breast cancers

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SLIT2, a human homologue of th ...... ted in lung and breast cancers

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SLIT2, a human homologue of th ...... ted in lung and breast cancers

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SLIT2, a human homologue of th ...... ted in lung and breast cancers

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SLIT2, a human homologue of th ...... ted in lung and breast cancers

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SLIT2, a human homologue of th ...... ted in lung and breast cancers

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SLIT2, a human homologue of th ...... ted in lung and breast cancers

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SLIT2, a human homologue of th ...... ted in lung and breast cancers

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Cancer Research

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Ashraf Dallol

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Eamonn R Maher

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Farida Latif

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Ivan Bieche

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John D Minna

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Paolo Viacava

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