Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells
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Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosisInsulin-like growth factor 1 receptor is a prognostic factor in classical Hodgkin lymphoma.Expression of insulin receptor substrate 1 in primary breast cancer and lymph node metastases.The therapeutic potential of agents targeting the type I insulin-like growth factor receptor.Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling.Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins.Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer.Transgenic overexpression of insulin receptor substrate 1 in hepatocytes enhances hepatocellular proliferation in young mice only.IGF-IR in neuroprotection and brain tumors.Depletion of insulin receptor substrate 2 reverses oncogenic transformation induced by v-src.Nuclear IRS-1 and cancerMutual interaction and reciprocal down-regulation between c-met and insulin receptor substrate-1.Estrogen receptor beta-mediated nuclear interaction between IRS-1 and Rad51 inhibits homologous recombination directed DNA repair in medulloblastomaRole of the insulin-like growth factor I/insulin receptor substrate 1 axis in Rad51 trafficking and DNA repair by homologous recombination.Nuclear insulin receptor substrate-1 activates promoters of cell cycle progression genes.Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling.Metastatic properties of prostate cancer cells are controlled by VEGF.Role of insulin receptor substrates and protein kinase C-zeta in vascular permeability factor/vascular endothelial growth factor expression in pancreatic cancer cells.MEK kinase 1 interacts with focal adhesion kinase and regulates insulin receptor substrate-1 expression.Nuclear translocation of insulin receptor substrate-1 by the simian virus 40 T antigen and the activated type 1 insulin-like growth factor receptor.Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines.Insulin receptor substrate 1 expression enhances the sensitivity of 32D cells to chemotherapy-induced cell death.Interaction between serine phosphorylated IRS-1 and beta1-integrin affects the stability of neuronal processesNuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis.
P2860
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P2860
Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells
description
2001 nî lūn-bûn
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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@ast
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@en
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@nl
type
label
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@ast
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@en
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@nl
prefLabel
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@ast
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@en
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@nl
P2093
P2860
P356
P1433
P1476
Mechanisms of regulation of ce ...... ate-1 in prostate cancer cells
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204112
P407
P577
2001-01-25T00:00:00Z
P5875
P6179
1046864690