Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake
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Identification of Murr1 as a regulator of the human delta epithelial sodium channelThe N-terminus of the human copper transporter 1 (hCTR1) is localized extracellularly, and interacts with itselfProjection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture.Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptakeHow Mammalian Cells Acquire Copper: An Essential but Potentially Toxic MetalCharting the travels of copper in eukaryotes from yeast to mammalsSynthetic fluorescent probes for studying copper in biological systemsSLC31 (CTR) family of copper transporters in health and diseaseA redox switch in CopC: An intriguing copper trafficking protein that binds copper(I) and copper(II) at different sitesA labile regulatory copper ion lies near the T1 copper site in the multicopper oxidase CueOIdentification of a vacuole-associated metalloreductase and its role in Ctr2-mediated intracellular copper mobilization.Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport systemCopper-stimulated endocytosis and degradation of the human copper transporter, hCtr1Copper is required for oncogenic BRAF signalling and tumorigenesisIdentification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporterCisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: requirement for the extracellular methionine-rich clustersCtr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domainIdentification of a receptor for an extinct virusA Plasmodium falciparum copper-binding membrane protein with copper transport motifsAn all-atom model of the structure of human copper transporter 1.C(alpha)-trace model of the transmembrane domain of human copper transporter 1, motion and functional implicationsCopper-dependent trafficking of the Ctr4-Ctr5 copper transporting complex.Ctr2 links copper homeostasis to polysaccharide capsule formation and phagocytosis inhibition in the human fungal pathogen Cryptococcus neoformans.Brachypodium distachyon as a model system for studies of copper transport in cereal cropsCopper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin.Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in riceA copper(I) protein possibly involved in the assembly of CuA center of bacterial cytochrome c oxidase.The role of the N-terminus of mammalian copper transporter 1 in the cellular accumulation of cisplatinThe role of the methionines and histidines in the transmembrane domain of mammalian copper transporter 1 in the cellular accumulation of cisplatinNovel transporter required for biogenesis of cbb3-type cytochrome c oxidase in Rhodobacter capsulatusHow copper traverses cellular membranes through the mammalian copper transporter 1, Ctr1.Ctr1 is an apical copper transporter in mammalian intestinal epithelial cells in vivo that is controlled at the level of protein stabilityThe role of Ctr1 and Ctr2 in mammalian copper homeostasis and platinum-based chemotherapy.Copper transporter 2 content is lower in liver and heart of copper-deficient rats.Regulation of Cisplatin cytotoxicity by cu influx transporters.Ripening in the tomato Green-ripe mutant is inhibited by ectopic expression of a protein that disrupts ethylene signaling.Copper and human health: biochemistry, genetics, and strategies for modeling dose-response relationships.Mechanisms for copper acquisition, distribution and regulation.The transport mechanism of bacterial Cu+-ATPases: distinct efflux rates adapted to different function.Mfc1 is a novel forespore membrane copper transporter in meiotic and sporulating cells.
P2860
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P2860
Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake
description
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im Juli 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 19 July 2002)
@en
vedecký článok (publikovaný 2002/07/19)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/07/19)
@nl
наукова стаття, опублікована в липні 2002
@uk
name
Biochemical and genetic analys ...... ed mechanism for copper uptake
@ast
Biochemical and genetic analys ...... ed mechanism for copper uptake
@en
Biochemical and genetic analys ...... ed mechanism for copper uptake
@nl
type
label
Biochemical and genetic analys ...... ed mechanism for copper uptake
@ast
Biochemical and genetic analys ...... ed mechanism for copper uptake
@en
Biochemical and genetic analys ...... ed mechanism for copper uptake
@nl
prefLabel
Biochemical and genetic analys ...... ed mechanism for copper uptake
@ast
Biochemical and genetic analys ...... ed mechanism for copper uptake
@en
Biochemical and genetic analys ...... ed mechanism for copper uptake
@nl
P2093
P2860
P356
P1476
Biochemical and genetic analys ...... ed mechanism for copper uptake
@en
P2093
Dennis J Thiele
Jaekwon Lee
Miranda Lau
P2860
P304
26021-26030
P356
10.1074/JBC.M202547200
P407
P50
P577
2002-04-30T00:00:00Z