Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test
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A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies.The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism.Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux.Endogenous nociceptin/orphanin-FQ in the dorsal hippocampus facilitates despair-related behavior.Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicidesNociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility.The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence.Nociceptin/orphanin FQ and NOP receptor gene regulation after acute or repeated social defeat stressUFP-112 a potent and long-lasting agonist selective for the Nociceptin/Orphanin FQ receptor.Social defeat disrupts reward learning and potentiates striatal nociceptin/orphanin FQ mRNA in rats.Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic-versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands.Usefulness of knockout mice to clarify the role of the opioid system in chronic pain.Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex.Further characterization of the prototypical nociceptin/orphanin FQ peptide receptor agonist Ro 64-6198 in rodent models of conflict anxiety and despair.Antidepressant activity of nociceptin/orphanin FQ receptor antagonists in the mouse learned helplessness.Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test.Rewarding or aversive effects of buprenorphine/naloxone combination (Suboxone) depend on conditioning trial duration.Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic
P2860
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P2860
Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Nociceptin receptor antagonist ...... the mouse forced swimming test
@ast
Nociceptin receptor antagonist ...... the mouse forced swimming test
@en
Nociceptin receptor antagonist ...... the mouse forced swimming test
@nl
type
label
Nociceptin receptor antagonist ...... the mouse forced swimming test
@ast
Nociceptin receptor antagonist ...... the mouse forced swimming test
@en
Nociceptin receptor antagonist ...... the mouse forced swimming test
@nl
prefLabel
Nociceptin receptor antagonist ...... the mouse forced swimming test
@ast
Nociceptin receptor antagonist ...... the mouse forced swimming test
@en
Nociceptin receptor antagonist ...... the mouse forced swimming test
@nl
P2093
P1476
Nociceptin receptor antagonist ...... the mouse forced swimming test
@en
P2093
Domenico Regoli
Girolamo Calo'
John P Redrobe
P2888
P356
10.1007/S00210-001-0511-0
P407
P50
P577
2002-02-01T00:00:00Z
P6179
1044648646