Fighting neurodegeneration with rapamycin: mechanistic insights
about
The associations between Parkinson's disease and cancer: the plot thickensMitochondrial biology and Parkinson's diseaseThe neurology of mTORProtein degradation pathways in Parkinson's disease: curse or blessingGenome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's diseaseHuman A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neuronsLarge FK506-Binding Proteins Shape the Pharmacology of RapamycinPotential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disordersDefective Autophagy, Mitochondrial Clearance and Lipophagy in Niemann-Pick Type B LymphocytesHow Parkinsonian toxins dysregulate the autophagy machineryDopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's diseaseAlleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegenerationSpermidine protects against α-synuclein neurotoxicity.Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer diseasePrenatal rapamycin results in early and late behavioral abnormalities in wildtype C57BL/6 miceThe transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.Protein misfolding specifies recruitment to cytoplasmic inclusion bodiesmTORC1 Is a Local, Postsynaptic Voltage Sensor Regulated by Positive and Negative Feedback Pathways.Myogenic differentiation of VCP disease-induced pluripotent stem cells: A novel platform for drug discoveryNeuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease.Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging.Mutations in the ATP13A2 gene and Parkinsonism: a preliminary review.Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients.Energy restriction and potential energy restriction mimetics.Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity.Alive and well? Exploring disease by studying lifespan.Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegenerationInduction of autophagy by a novel small molecule improves aβ pathology and ameliorates cognitive deficitsSubcellular distribution and activity of mechanistic target of rapamycin in aged retinal pigment epithelium.The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology.Suppressed autophagy flux in skeletal muscle of an amyotrophic lateral sclerosis mouse model during disease progression.Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy.Molecular chaperones in Parkinson's disease--present and futureSignaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents.The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease.The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy.Parkinson's disease: don't mess with calcium.
P2860
Q26778641-6780709A-D704-4200-A920-5F7D2CB19FA4Q26824090-74417F6A-36EF-4D05-A7D1-372E3A894E5DQ26824286-D4636415-CBD5-4182-AFDC-A05729AEE888Q27026029-833197B2-E5F2-40F5-A663-3246B9EC74D8Q27320372-B35C1EA3-DF31-4304-92E2-9E84DD41AC89Q27332460-D222F2CD-C349-4FD2-AD75-8C1B36962E8AQ27676039-5D066EFE-E459-4D2F-A7FD-33456A02388BQ28067037-A05D3F88-F232-4C4B-A7C2-5EDDA3F36769Q28109678-38DCCE6B-93E2-4FC4-BC5E-802F423CC79DQ28392567-3B1F528D-B9C3-4C56-9A28-3E816F104127Q28511558-CB0C791C-6E6A-46AF-BD9F-68D3DE0BFF14Q28834138-5A42C616-FE44-477D-9610-AFE8F94526DEQ30369463-CDE8A337-BB9F-4695-ACDE-B5B50191144BQ30412891-24FC2304-7410-4F8E-A5B8-9FC20184D243Q30444988-4D594FDA-81EC-46DD-9E0D-F0288EAEFFB1Q30524831-47878039-C00B-4980-9EEE-B63769BA367DQ30826780-42C5E9C2-1967-41C1-9B4F-92A76CF89F51Q33736580-CA81DE22-D8DA-4019-A686-AA49E861DBA5Q33757336-FE175783-24B5-4758-9386-5AB94CF4842FQ33775384-8D343765-551D-4FC2-B4AB-8B1B6FFE6C47Q33793017-78276F69-E672-4750-9AC4-B5175F05FD99Q33914286-55DEF273-C8B1-453F-B514-BA4EF15D6CFAQ33922676-8ECB6088-9874-4834-9A20-AD796F4D70F4Q34100399-BC576419-7F70-4193-AC7A-4E86F286FAB2Q34373059-C16D40FA-42F9-437E-8359-0DE448464C02Q34495145-8AC72CC0-BD1A-4FD8-B10F-8DC25A6D65E8Q34541372-3A99E88A-25F5-491F-8BD4-F4FB5931937AQ34542702-23E62950-0EFD-4B62-BCFF-D3252DB4BE21Q34618596-62A7CA60-86BF-4490-ABCE-F41C5551CD28Q34693311-4442C4DC-2F2F-4B36-8B81-6E7D5C0C2B37Q34764295-05D3FC74-ED9D-49E7-A59E-D84197418A18Q34795122-E0DE02A8-A0EE-4E19-839B-789FB0E4568FQ34950366-4BDE990D-196D-4B2E-8734-D6AA10BF830DQ35294409-8A58E6E8-2B20-4A12-BA07-44D424F4B722Q35462835-7809A71B-F7B5-4C2E-9221-344BB87E8929Q35688796-AC8C3950-6172-4363-AE7D-6EFACB8CAAC1Q35754079-9EB088EF-C1ED-4237-97C6-2E63BBE8820BQ35800000-E74E6715-3783-4A45-BE65-46944E443836Q35833536-E5D666AD-17DE-4BD6-8F1C-4457A6DBEC37Q35858158-BDAAE769-4376-4195-98CC-F3A48339BC9C
P2860
Fighting neurodegeneration with rapamycin: mechanistic insights
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Fighting neurodegeneration with rapamycin: mechanistic insights
@ast
Fighting neurodegeneration with rapamycin: mechanistic insights
@en
Fighting neurodegeneration with rapamycin: mechanistic insights
@nl
type
label
Fighting neurodegeneration with rapamycin: mechanistic insights
@ast
Fighting neurodegeneration with rapamycin: mechanistic insights
@en
Fighting neurodegeneration with rapamycin: mechanistic insights
@nl
prefLabel
Fighting neurodegeneration with rapamycin: mechanistic insights
@ast
Fighting neurodegeneration with rapamycin: mechanistic insights
@en
Fighting neurodegeneration with rapamycin: mechanistic insights
@nl
P3181
P356
P1476
Fighting neurodegeneration with rapamycin: mechanistic insights
@en
P2093
Jordi Bové
P2888
P304
P3181
P356
10.1038/NRN3068
P407
P577
2011-07-20T00:00:00Z
P6179
1001960200