Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation - sprookjes - yvandenbroek - TriplyDB

Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation

Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation

http://www.wikidata.org/entity/Q28247991

about

Palladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodeling Tumor stroma as targets for cancer therapy Palladin is upregulated in kidney disease and contributes to epithelial cell migration after injury The actin associated protein palladin in smooth muscle and in the development of diseases of the cardiovasculature and in cancer.The actin associated protein palladin is important for the early smooth muscle cell differentiation.Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury.The actin-associated protein Palladin is required for development of normal contractile properties of smooth muscle cells derived from embryoid bodies.TGF-β-elicited induction of tissue inhibitor of metalloproteinases (TIMP)-3 expression in fibroblasts involves complex interplay between Smad3, p38α, and ERK1/2.Isoform-specific upregulation of palladin in human and murine pancreas tumors.Elevated expression of stromal palladin predicts poor clinical outcome in renal cell carcinoma.Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton.Arousal of cancer-associated stroma: overexpression of palladin activates fibroblasts to promote tumor invasion.Akt2 regulates expression of the actin-bundling protein palladin Dual roles of palladin protein in in vitro myogenesis: inhibition of early induction but promotion of myotube maturation.Stromal Palladin Expression Is an Independent Prognostic Factor in Pancreatic Ductal Adenocarcinoma Redox-Sensitive Regulation of Myocardin-Related Transcription Factor (MRTF-A) Phosphorylation via Palladin in Vascular Smooth Muscle Cell Differentiation Marker Gene Expression Genomic and proteomic profiling II: comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation.Palladin contributes to invasive motility in human breast cancer cells The role of palladin in actin organization and cell motility.Cytoplasmic Ig-domain proteins: cytoskeletal regulators with a role in human disease Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence.The adventitia: Essential role in pulmonary vascular remodeling.Palladin regulation of the actin structures needed for cancer invasion.A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets.Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).Palladin expression is a conserved characteristic of the desmoplastic tumor microenvironment and contributes to altered gene expression.Structural characterization of the interactions between palladin and α-actinin Plasticity of fibroblasts demonstrated by tissue-specific and function-related proteome profiling.Response of fibroblasts to transforming growth factor-β1 on two-dimensional and in three-dimensional hyaluronan hydrogels.Identification and characterization of novel perivascular adventitial cells in the whole mount mesenteric branch artery using immunofluorescent staining and scanning confocal microscopy imaging.Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy.Phosphoinositide Binding Inhibits Actin Crosslinking and Polymerization by Palladin.Parkia pendula seed lectin: potential use to treat cutaneous wounds in healthy and immunocompromised mice.Palladin Compensates for the Arp2/3 Complex and Supports Actin Structures during Listeria Infections.Coexpression of myofibroblast and macrophage markers: novel evidence for an in vivo plasticity of chorioamniotic mesodermal cells of the human placenta.Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition.Topical TWEAK Accelerates Healing of Experimental Burn Wounds in Mice.

P2860

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P2860

Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation

http://www.wikidata.org/entity/Q28247991

description

2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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name

Isoform-specific regulation of ...... myofibroblast differentiation

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Isoform-specific regulation of ...... myofibroblast differentiation

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Isoform-specific regulation of ...... myofibroblast differentiation

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Isoform-specific regulation of ...... myofibroblast differentiation

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Isoform-specific regulation of ...... myofibroblast differentiation

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Journal of Investigative Dermatology

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Isoform-specific regulation of ...... myofibroblast differentiation

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Andrew Rachlin

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Carol A Otey

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Mikko J Rönty

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Olli M Carpén

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Veli-Matti Kähäri

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2387-96

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scholarly article

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2259699

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10.1038/SJ.JID.5700427

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11

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126

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Suvi-Katri Leivonen

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2006-11-01T00:00:00Z

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6989120

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1019934838

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16794588

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