Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
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A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in miceRapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevityEndocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouseSingle-gene mutations and healthy ageing in mammalsGrowth hormone and aging: a challenging controversyRole of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models.FOXO3A genotype is strongly associated with human longevityKlotho and agingInter-organelle ER-endolysosomal contact sites in metabolism and disease across evolutionUnraveling the message: insights into comparative genomics of the naked mole-ratGenetics and epigenetics of aging and longevityAging signaling pathways and circadian clock-dependent metabolic derangementsModelling age-related metabolic disorders in the mouseDoes reduced IGF-1R signaling in Igf1r+/- mice alter aging?Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanismA potential link between phosphate and aging--lessons from Klotho-deficient miceNaturally occurring p16(Ink4a)-positive cells shorten healthy lifespanKlotho: a humeral mediator in CSF and plasma that influences longevity and susceptibility to multiple complex disorders, including depressionLongevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intakeMinireview: The Complexities of IGF/Insulin Signaling in Aging: Why Flies and Worms Are Not HumansThe somatotropic axis and longevity in miceDepletion of Rictor, an essential protein component of mTORC2, decreases male lifespanGrowth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in miceDeletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic miceBig mice die young but large animals live longerAging and the Mammalian regulatory triumvirateInsights from comparative analyses of aging in birds and mammalsEnergetics and longevity in birdsRibosomal protein S6 kinase 1 signaling regulates mammalian life spanShould we treat aging as a disease? The consequences and dangers of miscategorisation.'Adipaging': ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue.Small is beautiful: insulin-like growth factors and their role in growth, development, and cancerDeletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.Statement by the Growth Hormone Research Society on the GH/IGF-I axis in extending health span.Behavioral Senescence and Aging-Related Changes in Motor Neurons and Brain Neuromodulator Levels Are Ameliorated by Lifespan-Extending Reproductive Dormancy in Drosophila.Ppargamma2 is a key driver of longevity in the mouse.Maternal protein restriction affects postnatal growth and the expression of key proteins involved in lifespan regulation in mice.A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study.Disruption of protein kinase A in mice enhances healthy aging.The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity.
P2860
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P2860
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@ast
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@en
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@nl
type
label
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@ast
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@en
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@nl
prefLabel
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@ast
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@en
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@nl
P2093
P50
P3181
P356
P1433
P1476
Evidence for lifespan extensio ...... receptor substrate 1 null mice
@en
P2093
Agharul I Choudhury
Danielle Carmignac
Eric Blanc
Hind Al-Qassab
Iain C A Robinson
John R Speakman
Melanie Clements
Steven Lingard
P304
P3181
P356
10.1096/FJ.07-9261COM
P407
P50
P577
2008-03-01T00:00:00Z