Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
about
Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapySecretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammalsChemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathwayHedgehog signaling pathway in colorectal cancer: function, mechanism, and therapy.A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12.Inhibition of tumor formation and redirected differentiation of glioblastoma cells in a xenotypic embryonic environment.Large differences in global transcriptional regulatory programs of normal and tumor colon cellsGli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy.Oncogenesis and induced pluripotency - commonalities of signalling pathwaysThe heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics.DLAT subunit of the pyruvate dehydrogenase complex is upregulated in gastric cancer-implications in cancer therapyDiindolylmethane-mediated Gli1 protein suppression induces anoikis in ovarian cancer cells in vitro and blocks tumor formation ability in vivo.Dysregulation of hedgehog signaling pathway related components in the evolution of colonic carcinogenesis.In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases.Specific requirement of Gli transcription factors in Hedgehog-mediated intestinal development.GLI1 upregulates C-JUN through a specific 130-kDa isoformPeroxiredoxin 2 is essential for maintaining cancer stem cell-like phenotype through activation of Hedgehog signaling pathway in colon cancer.Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch.The Hedgehog signal transduction network.Nonclassical hedgehog-GLI signaling and its clinical implications.Inhibition of Hedgehog signaling in the gastrointestinal tract: targeting the cancer microenvironment.Hedgehog signaling pathway as key player in liver fibrosis: new insights and perspectives.Identifying hedgehog signaling specific microRNAs in glioblastomas.Opposite activation of the Hedgehog pathway in CD138+ plasma cells and CD138-CD19+ B cells identifies two subgroups of patients with multiple myeloma and different prognosis.DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis.Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress.Recent advances in understanding the roles of whole genome duplications in evolution.Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma.Sonic Hedgehog Signaling in Thyroid Cancer.Truncated glioma-associated oncogene homolog 1 (tGLI1) mediates mesenchymal glioblastoma via transcriptional activation of CD44.Gli3 is a negative regulator of Tas1r3-expressing taste cells.Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma.Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway.
P2860
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P2860
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@ast
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@en
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@nl
type
label
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@ast
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@en
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@nl
prefLabel
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@ast
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@en
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@nl
P2860
P1433
P1476
Hedgehog signaling and the Gli code in stem cells, cancer, and metastases
@en
P2093
Ariel Ruiz i Altaba
P2860
P356
10.1126/SCISIGNAL.2002540
P407
P577
2011-11-22T00:00:00Z