Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
about
Differential regulation of telomerase activity by six telomerase subunitsPinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual rolesIncreased Stability of Nucleolar PinX1 in the Presence of TERTTherapeutic efficacy of PUMA for malignant glioma cells regardless of p53 status.Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 bindingTelomere shortening and apoptosis in telomerase-inhibited human tumor cellsInvolvement of 14-3-3 proteins in nuclear localization of telomerasehTERT protein expression is independent of clinicopathological parameters and c-Myc protein expression in human breast cancerStrict control of telomerase activation using Cre-mediated inversion.SPECT/CT imaging of hNIS-expression after intravenous delivery of an oncolytic adenovirus and 131IMolecular interactions between telomerase and the tumor suppressor protein p53 in vitroTelomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivoInhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinomaRole of Smad3 in the regulation of rat telomerase reverse transcriptase by TGFbetaThe hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironmentA mutant of Tetrahymena telomerase reverse transcriptase with increased processivity.Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax.mRNA quantification and clinical evaluation of telomerase reverse transcriptase subunit (hTERT) in intracranial tumours of patients in the island of Crete.Telomerase activity, estrogen receptors (alpha, beta), Bcl-2 expression in human breast cancer and treatment responseActions of heparin that may affect the malignant process.The protein subunit of telomerase displays patterns of dynamic evolution and conservation across different metazoan taxa.Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma.Telomerase and hTERT: can they serve as markers for gastric cancer diagnosis?Telomerase Inhibitory Effects of Red Pigment Rubropunctatin and Statin Monacolin L Isolated from Red Yeast Rice.Molecular-pathological diagnosis of gastrointestinal tissues and its contribution to cancer histopathology.The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalizationDownstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repressionDevelopmentally regulated telomerase activity is correlated with chromosomal healing during chromatin diminution in Ascaris suum.Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro.Zinc finger protein 637 protects cells against oxidative stress-induced premature senescence by mTERT-mediated telomerase activity and telomere maintenance.Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering.N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo.InTERTpreting telomerase structure and functionIncreased placental telomerase mRNA in hypertensive disorders of pregnancyTelomerase activation, cellular immortalization and cancer.C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity.Telomere maintenance mechanisms as a target for drug development.The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activityComplex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy?
P2860
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P2860
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@ast
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@en
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@nl
type
label
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@ast
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@en
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@nl
prefLabel
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@ast
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@en
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@nl
P2093
P3181
P356
P1433
P1476
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
@en
P2093
F Ishikawa
H Nakamura
J Nakayama
T Nakanishi
P2888
P3181
P356
10.1038/NG0198-65
P407
P577
1998-01-01T00:00:00Z